8 citations
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November 1978 in “British journal of dermatology/British journal of dermatology, Supplement” Cyproterone acetate can effectively treat idiopathic hirsutism, but ethinyl oestradiol and lynoestrenol may not always reduce hair growth.
1 citations
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January 2013 in “UNICA IRIS Institutional Research Information System (University of Cagliari)” Hormonal contraceptives may reduce social behavior and sexual motivation by lowering allopregnanolone levels.
January 2026 in “Journal of Sexual and Mental Health” New male contraceptive pills show promise in reducing sperm production with mild side effects.
6 citations
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April 2004 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New progesterone-based compounds can block male hormones.
1 citations
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June 2022 in “JAAD case reports” A woman developed a severe skin reaction after getting a birth control implant.
186 citations
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December 2011 in “Molecules” Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
5 citations
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November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
The FDA did not approve a testosterone drug because of safety concerns.
3 citations
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July 2009 in “Experimental and Clinical Endocrinology & Diabetes” Low-dose Buserelin effectively reduces hirsutism with minimal side effects.
October 2024 in “Journal of the Endocrine Society” Estrogen alone may effectively suppress testosterone in some transfeminine individuals.
78 citations
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October 2003 in “Cochrane library” Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
64 citations
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January 1985 in “Clinical endocrinology” A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.
42 citations
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May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
October 2024 in “Journal of the Endocrine Society” Estrogen alone can lower testosterone in some transfeminine people.
11 citations
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November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
July 2024 in “Reactions Weekly”
2 citations
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December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
2 citations
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August 2013 in “The Lancet. Diabetes & endocrinology” The FDA rejected a testosterone drug again due to safety concerns.
4 citations
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December 1994 in “PubMed” Cyproterone acetate with estradiol improved women's self-confidence and emotional well-being without a difference between oral or transdermal methods, but younger women preferred the oral method.
22 citations
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March 2000 in “Clinical endocrinology” Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.
1 citations
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January 2010 in “Endocrine abstracts”
1 citations
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January 2004 in “Drugs” Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.
14 citations
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June 2011 in “Steroids” New compounds may help treat prostate issues without affecting androgen receptors.
33 citations
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January 1979 in “Acta obstetricia et gynecologica Scandinavica” Diane® is an effective contraceptive that also helps treat acne and mild hair growth issues.
36 citations
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
20 citations
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January 2003 in “Chemical and Pharmaceutical Bulletin” The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
31 citations
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January 2001 in “PubMed” January 2006 in “Xibei zhiwu xuebao” Norethindrone and levonorgestrel can enhance or inhibit root growth in Arabidopsis thaliana depending on the concentration.
59 citations
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September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
8 citations
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January 1996 in “Gynecological Endocrinology” Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.