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Early Postnatal Neuroactive Steroid Manipulation Differentially Affects Recognition Memory and Passive Avoidance Performance in Male Rats

research Early postnatal neuroactive steroid manipulation differentially affects recognition memory and passive avoidance performance in male rats

2 citations , July 2020 in “Behavioural Brain Research”

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

research Efficacy and Safety of SER120 Nasal Spray in Patients with Nocturia: Pooled Analysis of 2 Randomized, Double-Blind, Placebo Controlled, Phase 3 Trials

21 citations , April 2018 in “The Journal of urology/The journal of urology”

SER120 nasal spray effectively reduces nighttime urination and is safe for patients.

research Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist

9 citations , April 2021 in “Expert opinion on pharmacotherapy”

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Molecular Docking of Vitamin D3 Receptor with Potential Herbal Substances as Ligands to Prevent Excessive Hair Loss in Menopausal Women

research Molecular docking of Vitamin D3 Receptor (VDR) with potential herbal substance as ligand to prevent excessive hair loss in menopausal women

August 2022 in “Indonesian Journal of Medical Chemistry and Bioinformatics”

Certain herbal compounds might help prevent hair loss in menopausal women by activating Vitamin D receptors.

research Progesterone-induced spike-wave discharges are inhibited by finasteride

January 2004 in “Data Archiving and Networked Services (DANS)”

Finasteride blocks progesterone's effect on brain activity linked to epilepsy.

Finasteride, a 5α-Reductase Inhibitor, Potentiates Antinociceptive Effects of Morphine, Prevents the Development of Morphine Tolerance and Attenuates Abstinence Behavior in the Rat

research Finasteride, a 5α-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat

15 citations , March 2007 in “Hormones and Behavior”

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice

9 citations , November 1997 in “British Journal of Dermatology”

research Pharmaceutical and Pharmacological Evaluation of the Effect of Nano-Formulated Spironolactone and Progesterone on Inflammation and Hormonal Levels for Managing Hirsutism Experimentally Induced in Rats

15 citations , July 2021 in “AAPS PharmSciTech”

research Dutasteride

January 2025

Dutasteride may become the top choice for treating hair loss.

research Dutasteride/finasteride

April 2022 in “Reactions Weekly”

research The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids

2 citations , September 2009 in “Hormone Molecular Biology and Clinical Investigation”

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Antiandrogen Treatment with Spironolactone and Linestrenol Decreases Bone Mineral Density in Eumenorrhoeic Women with Androgen Excess

research Antiandrogen Treatment with Spironolactone and Linestrenol Decreases Bone Mineral Density in Eumenorrhoeic Women with Androgen Excess

26 citations , January 1994 in “Hormone and Metabolic Research”

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.

research FDA declines approval of testosterone drug for third time

January 2013

The FDA did not approve a testosterone drug because of safety concerns.

Drug Interactions Between Common Dermatological Medications and the Oral Anti-Covid-19 Agents Nirmatrelvir-Ritonavir and Molnupiravir

research Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir

5 citations , December 2022 in “Annals Academy of Medicine Singapore”

Some skin medications can have harmful interactions with the COVID-19 drug nirmatrelvir-ritonavir, but not with molnupiravir.

research Clascoterone as a novel treatment for androgenetic alopecia

5 citations , May 2020 in “Clinical and Experimental Dermatology”

Clascoterone may be a promising treatment for hair loss.

research The neurosteroid metabolite of progesterone, 3α‐OH‐dihydroprogesterone (3α‐OH‐DHP), is required for attenuated baroreflex mediated sympathoexcitation in pregnancy

1 citations , April 2013 in “The FASEB Journal”

3α‐OH‐DHP is essential for reducing nerve activity related to blood pressure control during pregnancy.

research Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus

19 citations , September 2006 in “Journal of Neurophysiology”

Neurosteroids help balance brain signals when certain inhibitions are reduced.

research Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics

December 2022 in “Scientific Reports”

Compound 4 is a promising treatment for hair loss with low toxicity.

Progesterone-Independent Neurosteroid Regulation of Alpha2-GABA-A Receptors in the Hippocampus Subfields

research PR-independent neurosteroid regulation of α2-GABA-A receptors in the hippocampus subfields

14 citations , March 2017 in “Brain research”

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target

research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target

3 citations , April 2021 in “Journal of Medicinal Chemistry”

Finasteride may affect PNMT, causing side effects.

research 5‐Alpha reductase inhibitors in androgenetic alopecia: Shifting paradigms, current concepts, comparative efficacy, and safety

19 citations , April 2020 in “Dermatologic Therapy”

Dutasteride works better than finasteride for hair loss, with both being safe to use.

research [Contraceptive methods for adolescents].

October 1985 in “PubMed”

Oral contraceptives are generally recommended for healthy young girls, but specific types may vary based on individual health conditions and barrier methods are less popular among adolescents.