Correcting EDA fibronectin organization and YAP translocation can improve wound healing in fibrotic conditions.
October 2022 in “Research Square (Research Square)” Key genes linked to immune response are highly active in lupus-affected hair follicles.
November 2015 in “European Journal of Inflammation” Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
January 2023 in “Open Life Sciences” VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.
88 citations
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May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
53 citations
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June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
32 citations
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May 2015 in “Journal of Investigative Dermatology” Mice without collagen VI have slower hair growth normally but faster regrowth after injury.
May 2014 in “Transfusion and Apheresis Science” Multiple plasma donations do not change donors' biochemical parameters.
March 2012 in “Journal of The American Academy of Dermatology” Temporal triangular alopecia usually starts in early childhood and treatment with Minoxidil has limited effectiveness.
3 citations
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March 2020 in “Dermatology Research and Practice” Tracnil™, a mix of myo-inositol, folic acid, and vitamin D3, safely reduced acne, improved excessive hair growth, and fixed irregular periods in overweight women with PCOS.
January 2022 in “Indian journal of dermatopathology and diagnostic dermatology” Women with diffuse hair loss often have lower iron and vitamin D levels, but their thyroid function is typically normal.
28 citations
,
August 2018 in “BMC genomics” DNA methylation changes are linked to hair growth cycles in goats.
73 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
14 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
11 citations
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March 2001 in “Clinics in Dermatology” Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
1 citations
,
May 2018 in “jurnal veteriner” Scraping is the best method to diagnose demodicosis in dogs.
Hair follicles can be used to quickly assess drug effects in cancer treatment.
68 citations
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March 2018 in “Biomaterials” Tiny needles with valproic acid can effectively regrow hair.
44 citations
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September 2012 in “Archives of Dermatology” Hair breakage may be an early sign of a hair loss condition called CCCA in African American women.
15 citations
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February 1999 in “The anatomical record” Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.
4 citations
,
January 1976 in “Archives of Dermatological Research” Metabolic disorders can cause hair structure defects and growth issues, but amino acid levels in hair remain normal.
2 citations
,
January 1984 in “Progress in neuro-psychopharmacology & biological psychiatry” Benzodiazepines changed hormone levels but did not affect hair growth in women with idiopathic hirsutism.
1 citations
,
January 2016 in “International journal of research in ayurveda and pharmacy” The study found that a specific combination of five medicinal plants effectively inhibits the fungus that causes dandruff.
31 citations
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January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
211 citations
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April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
91 citations
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December 2010 in “Stem Cells” Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
53 citations
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November 2006 in “Journal of Endocrinology” Prolactin slows down hair growth in mice.
46 citations
,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
34 citations
,
April 2016 in “International Journal of Dermatology” Trichoscopy is a useful method for identifying primary cicatricial alopecias and their specific types.
11 citations
,
February 2008 in “British journal of nursing” Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.