37 citations
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September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
10 citations
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February 2017 in “European journal of neuroscience/EJN. European journal of neuroscience” The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.
33 citations
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October 2005 in “PubMed” Dutasteride successfully treated a woman's hair loss when other treatments failed.
January 2009 in “Chemical Reagents” The method produces finasteride with a 92% yield.
29 citations
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April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
24 citations
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January 2017 in “International Journal of Trichology”
January 2021 in “Social Science Research Network” The new treatment using tiny lipid carriers to deliver minoxidil and latanoprost directly to hair follicles shows promise for alopecia.
12 citations
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February 1975 in “Journal of Steroid Biochemistry” January 2011 in “Zhongguo xin yao zazhi” A new, safer method to make finasteride from progesterone is effective for industrial use.
November 2022 in “Journal of the Endocrine Society” Long-term treatment with buprenorphine/naloxone for opioid addiction may lead to secondary adrenal insufficiency.
15 citations
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October 2014 in “Hormone Molecular Biology and Clinical Investigation” Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
45 citations
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January 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
December 2024 in “PubMed” TrichoFoam™ effectively delivers multiple hair loss treatments, maintaining their stability and effectiveness.
The 0.05% dutasteride topical solution effectively promotes hair growth with fewer side effects than oral treatments.
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
15 citations
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April 2016 in “Hormones” Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
17 citations
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January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
25 citations
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December 2009 in “Developmental Neurobiology” Androgens are essential for maintaining adult neuromuscular structure.
13 citations
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November 2005 in “Epilepsia” Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.
2 citations
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December 2008 in “Journal of Chemical Crystallography” The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
1 citations
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January 2021 in “European Journal of Inflammation” Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
23 citations
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February 2010 in “European Journal of Medicinal Chemistry” May 2008 in “10th European Congress of Endocrinology”
20 citations
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January 1999 in “Current Pharmaceutical Design” Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.
25 citations
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January 1978 in “JAMA” Topical corticosteroids can cause serious side effects like Cushing's syndrome and hirsutism.
11 citations
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July 2020 in “Journal of Cosmetic Dermatology” Sandalore® improves hair growth and quality in people with hair loss.
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January 1997 in “Biochemical Pharmacology” Human liver enzyme DHEA ST helps process minoxidil.
11 citations
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September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
September 2002 in “Epiliepsy currents/Epilepsy currents” Stress increases neurosteroids that help prevent seizures.