research The involvement of Elf5 in regulating keratinocyte proliferation and differentiation processes in skin
Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
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990-1000 / 1000+ results research Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 MKG2D Lymphocytes of Alopecia Areata Patients
EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
research MAD2B acts as a negative regulatory partner of TCF4 on proliferation in human dermal papilla cells
MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.
research The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
Nephronectin helps attach muscle cells to hair follicles.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research Stem Cell Therapy for Burns: Story so Far
Stem cell therapy shows promise in improving burn wound healing.
research Age and Sex-Related Changes to Gene Expression in the Mouse Spinal Cord
research Intrinsic factors in the pathogenesis of hidradenitis suppurativa: Genetics, hormones, and the microbiome
This review examines the complex pathogenesis of hidradenitis suppurativa (HS), focusing on genetic, hormonal, and microbiome factors. It identifies genetic links to hair follicle stem cell fate and androgen signaling, with inflammation influenced by the cutaneous and gut microbiomes. Hormonal factors, particularly during puberty and pregnancy, and metabolic factors like obesity and insulin resistance, are highlighted as contributors to HS. The review notes the altered microbiome in HS patients and suggests that a combination of therapies targeting hormonal, metabolic, and immunological factors may improve clinical outcomes. However, it emphasizes the need for further research to address unresolved questions about disease predisposition and progression.
research Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo
Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.
research Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways
Mathematical modeling helps understand and predict the MAPK cell signaling pathway.