32 citations
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January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
30 citations
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September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
30 citations
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April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
30 citations
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August 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect hormone levels in normal men.
29 citations
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May 2018 in “Clinical Endocrinology” Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
29 citations
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September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
28 citations
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September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
27 citations
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March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
26 citations
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June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
26 citations
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February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
26 citations
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January 1994 in “Clinics in Dermatology” Artificial skin is improving wound healing and shows potential for treating different types of wounds.
25 citations
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December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
25 citations
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June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
25 citations
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January 2002 in “Folia Pharmacologica Japonica” Minoxidil helps hair grow by improving blood flow and increasing growth factors in hair follicles.
25 citations
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March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
24 citations
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March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
24 citations
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May 2010 in “Veterinary dermatology” Oral ciclosporin A and topical treatments both reduce hair loss and scaling in dogs with sebaceous adenitis, but using both together is most effective.
24 citations
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September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
23 citations
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September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
23 citations
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April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
22 citations
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January 2021 in “Pharmacognosy Journal” These three weeds have important medicinal properties and need more research for potential pharmaceutical use.
22 citations
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October 2020 in “Anais Brasileiros de Dermatologia” The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.
22 citations
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March 2020 in “Journal of The American Academy of Dermatology” DSC cell injections significantly improved hair density and diameter, showing potential as a hair loss treatment.
22 citations
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November 1998 in “Archives of Dermatology” Alternative medicine lacks scientific support and relies on the placebo effect, but remains popular and integrated into German healthcare.
21 citations
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July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
21 citations
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March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
21 citations
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April 2010 in “Veterinary Dermatology” Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
20 citations
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November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.