research Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats
Inhibiting certain enzymes made female rats more sensitive to low-level pain.
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research Topical lotion beneficial in androgenetic alopecia
Lotion with piroctone olamine and triclosan improves hair loss in men.
research Design, synthesis and structure-activity relationships studies on steroidal aromatase and 5α-reductase inhibitors as anti-tumors
Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.
research 708 SIG-1451: A topical anti-inflammatory new chemical entity for atopic dermatitis (AD)
SIG-1451 could be a promising new treatment for atopic dermatitis.
research Effect of Various Herbal and Chemical Enhancers on Skin Permeability to Cetirizine: A Study of Changes in Rat Skin Cells
Eucalyptus and Tween 80 most effectively increase cetirizine skin absorption.
research ANTIANDROGENS AND THE SKIN
Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.
research Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research 837 Characterization of cutaneous hormone production through analysis of skin secretions
Skin produces different hormones depending on body part and sex, and a new method can measure them.
research BIOLOGICAL ACTIVITY OF ANTIANDROGENS
Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research Prooxidant and antioxidant action of 4-(4-phenoxybenzoyl)benzoic acid derivatives
4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.
research Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles
A PEG-400/oleic acid mixture best improves drug delivery monitoring through hair follicles.
research Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Skin development in the gray short‐tailed opossum (Monodelphis domestica)—From skin respiration to thermoregulation
Gray short-tailed opossums' skin shifts from helping with breathing to regulating body temperature as they grow.
research Non-comedogenic and non-acnegenic hair and scalp care formulations and method for use
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Effect of surfactant type on the dyeability and color resistance of semi-permanent basic hair dye
Cationic and nonionic surfactants provide better color intensity and resistance for semi-permanent hair dye than anionic surfactants.
research Crude extracts and essential oil of Platycladus orientalis (L.) Franco: a source of phenolics with antioxidant and antibacterial potential as assessed through a chemometric approach
Platycladus orientalis essential oil and ethanol extracts can be effective natural antioxidants and antibacterial agents.
research Disruptors of Androgen Action and Synthesis
Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
research Adrenal steroid precursors exert potent androgenic action in the hamster sebaceous glands of flank organs and ears.
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research Quality Analysis of Shampoo Based on Rosemary Essential Oil (Rosmarinus officinalis L.) Concentration
The 2% rosemary oil shampoo was the best overall.
research Comparison of comedolytic effect of benzoyl peroxide and adapalene in rhino mice
Benzoyl peroxide and adapalene gels work differently to reduce acne in mice.
research Hair Growth Stimulation in Testosterone-Induced Alopecic Mice: A Comparative Study between Topical Clove Oil 10% Topical Minoxidil 5% Research ArticleJournal of the Faculty of Medicine BaghdadPrint ISSN: 0041-9419, Online ISSN: 2410-8057DOI: https://doi.org/10.32007/jfacmedbaghdad2977. Hair Growth Stimulation in Testosterone-Induced Alopecic Mice: A Comparative Study between Topical Clove oil 10% Topical Minoxidil 5%
Clove oil may help hair growth like minoxidil, but more human tests are needed.
research 17α-Acetoxy-6-bromo-16β-methylpregna-4,6-diene-3,20-dione
A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
research Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia
LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.
research Formulasi dan Evaluasi Aktivitas Antijamur Gel Sampo Anti ketombe Minyak Sereh Dapur (Cymbopogon citratus)
Lemongrass oil in gel shampoo effectively fights dandruff, with 10% concentration being the most effective.
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Pengaruh Pertumbuhan Rambut Menggunakan Hair Tonic dengan Penambahan Ekstrak Rosemary Secara In Vivo
Rosemary extract hair tonic is a safe and effective natural alternative for promoting hair growth.
research Chemical examination of three Indian medicinal plants and their hair growth evaluation studies
Three Indian medicinal plant compounds help hair growth.