4 citations
,
August 2011 in “The Lancet Oncology” Off-label drug use can be risky and requires careful consideration to ensure patient safety.
January 2020 in “Current trends in diagnosis & treatment” The review suggests doctors should carefully weigh risks and benefits of off-label drug use, involve patients in decisions, and calls for better regulations and monitoring.
8 citations
,
August 2018 in “International Journal of Dermatology” The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.
3 citations
,
January 2015 in “Social Science Research Network” The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.
3 citations
,
February 2019 in “International Journal of Community Medicine and Public Health” Most off-label drug prescriptions in Saudi Arabia are for adults with depression and diabetes.
2 citations
,
June 2020 in “BMC Health Services Research” Health warnings and public health actions led to a significant drop in flutamide prescriptions for women, but off-label use still continues.
1 citations
,
January 2024 in “Curēus” Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
10 citations
,
May 2020 in “Journal of The American Academy of Dermatology” Taking spironolactone doesn't increase the chance of breast cancer coming back.
July 2020 in “Journal of the American Academy of Dermatology” Spironolactone does not increase the risk of breast cancer recurrence.
2 citations
,
August 2016 in “British Journal of Clinical Pharmacology” The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.
32 citations
,
January 2019 in “American Journal of Clinical Dermatology” Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Patients with alopecia areata face challenges accessing Janus kinase inhibitors, but some see positive results.
50 citations
,
March 2021 in “Journal of investigational allergology & clinical immunology” Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
1 citations
,
April 2025 in “Experimental Dermatology” Topical ruxolitinib may help some skin conditions but needs more research for alopecia areata.
February 2026 in “Biomedicines” Off-label treatments are heavily used for alopecia areata due to limited approved options.
September 2025 in “Healthcare” SSRIs may help manage sexual behavior in dementia patients, but they can cause long-lasting sexual dysfunction.
April 2020 in “Online journal of complementary & alternative medicine” Some medications can help increase sexual desire and function in women.
2 citations
,
March 2018 in “Journal of The American Academy of Dermatology” Doctors should prescribe cheaper, off-label medication and teach patients how to use it to save money ethically.
2 citations
,
July 2022 in “Journal of the American Academy of Dermatology” The safety and tolerability of low-dose oral minoxidil for treating hair loss in adolescents is not clearly determined.
June 2023 in “International journal of biology, pharmacy and allied sciences” New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.
August 2012 in “Pharmaceutical Medicine” The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
30 citations
,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
5 citations
,
October 2012 in “Journal of Midwifery & Women's Health” Healthcare providers should start with simple fertility tests and treatments before referring patients to specialists.
22 citations
,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
2 citations
,
May 2001 in “Current problems in dermatology” The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.
28 citations
,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
6 citations
,
May 2011 in “Journal of Pharmacy Technology” Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.
1 citations
,
March 2013 in “The European Journal of Contraception & Reproductive Health Care” The paper suggests that France's suspension of Diane-35 was hasty and could cause treatment issues and unintended pregnancies, recommending a re-evaluation and better patient information.
1 citations
,
April 1987 in “American Journal of Nursing” Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
39 citations
,
January 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.