421 citations
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January 2015 in “Chemical Society Reviews” Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
263 citations
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February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” Polymeric nanoparticles show promise for treating skin diseases.
211 citations
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June 2012 The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
170 citations
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September 2019 in “Evidence-based Complementary and Alternative Medicine” Some medicinal plants can help heal wounds and may lead to new treatments.
156 citations
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August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
143 citations
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April 2018 in “Electronic physician” More research is needed to confirm safflower's traditional medicinal uses.
130 citations
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August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
128 citations
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July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
112 citations
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November 2023 in “Nano-Micro Letters” Nanozymes show promise for effective and safe cancer treatment.
104 citations
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January 2016 in “Food & Function” Olive oil compounds may help prevent cancer in animals, but human results are mixed.
101 citations
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October 2013 in “Journal of The Saudi Pharmaceutical Society” Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.
94 citations
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September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
89 citations
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November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
86 citations
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July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
84 citations
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April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
82 citations
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January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
72 citations
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January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
68 citations
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May 2011 in “European Journal of Dermatology” Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
67 citations
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June 2018 in “Engineering in Life Sciences” Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
64 citations
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March 2006 in “Food Chemistry” The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
58 citations
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November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
54 citations
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October 2024 in “Nature Communications” Molybdenum oxide nanozymes can effectively treat and monitor acute kidney injury by reducing oxidative stress.
52 citations
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January 2020 in “Scientific Reports” NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
51 citations
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January 2024 in “Nanoscale” Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
51 citations
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October 2012 in “International Journal of Immunopathology and Pharmacology” Finasteride works better than Serenoa repens for male hair loss.
49 citations
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September 2008 in “International journal of pharmaceutics” Artificial sebum L closely mimics human sebum for drug delivery research.
48 citations
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January 2018 in “Scientific Reports” Hair analysis can reveal metabolic changes and potential pregnancy complications.
48 citations
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September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
47 citations
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March 2022 in “Frontiers in cellular and infection microbiology” Changes in skin microbes play a role in some skin diseases and could lead to new treatments.