236 citations
,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
199 citations
,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
125 citations
,
May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
124 citations
,
June 2002 in “Best Practice & Research Clinical Endocrinology & Metabolism” Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.
105 citations
,
February 1996 in “Journal of biological chemistry/The Journal of biological chemistry” The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
75 citations
,
January 2014 in “Archiv Der Pharmazie” Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
61 citations
,
November 2020 in “Molecules” Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.
42 citations
,
May 2013 in “Oral Diseases” Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.
30 citations
,
December 2018 in “International Journal of Biological Macromolecules” Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.
29 citations
,
February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
25 citations
,
August 2010 in “Acta Biomaterialia” Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
18 citations
,
July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
10 citations
,
May 2021 in “Expert Opinion on Drug Delivery” Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.
8 citations
,
October 2019 in “Immunological investigations” The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.
7 citations
,
May 2016 in “European Polymer Journal” The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
7 citations
,
November 2010 in “Genesis” Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
6 citations
,
May 1997 in “Journal of Dermatological Science” Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
5 citations
,
June 2013 in “Fashion business” Rosehip extract improves hair wave, thickness, and color vibrancy.
3 citations
,
June 2020 in “Developmental Cell” Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.
3 citations
,
October 2009 in “Iranian Journal of Basic Medical Sciences” Buxus wallichiana extract improves hair growth and has antioxidant properties, with oral use more effective than topical.
2 citations
,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
2 citations
,
March 2014 in “Journal of Korean Medicine” Standardized rules are needed for consistent Romanized prescription names in Korean Traditional Medicine.
1 citations
,
October 2021 in “Gene, cell and tissue” Grape sap may help reduce hair loss and promote hair growth in rats.
1 citations
,
November 2014 in “British journal of medicine and medical research” PCOS and related metabolic issues often run in families.
1 citations
,
October 2001 in “Journal of Wood Science” Some extracts from woods and fungi can promote hair growth better than a known hair growth substance.
November 2021 in “Research, Society and Development” Individualized treatment and psychological support are crucial for alopecia.
January 2017 in “Korean Journal of Pharmacognosy” Modified red ginseng extract promotes hair growth and has antioxidant and anti-inflammatory effects.
January 2015 in “Hair therapy & transplantation” Some botanical products may help increase hair growth in people with alopecia, but more research is needed.
January 2002 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.
October 2001 in “WORLD SCIENTIFIC eBooks” Many substances, including chemicals and metals, can cause skin reactions; careful handling and identification of allergens are crucial to prevent dermatitis.