53 citations
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January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
51 citations
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July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
50 citations
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March 2017 in “PeerJ” Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
49 citations
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July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
48 citations
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July 2018 in “Journal of The American Academy of Dermatology” Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.
48 citations
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September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
46 citations
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June 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
41 citations
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October 2012 in “Australian and New Zealand Journal of Psychiatry” Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
40 citations
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December 2019 in “Neurobiology of Stress” Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
39 citations
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June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” Plant-based ingredients are effective and safe for modern skincare products.
38 citations
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April 2018 in “Psychopharmacology/Psychopharmacologia” Blocking CRF-R1 can reduce alcohol intake in stressed mice.
38 citations
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June 2015 in “Expert Opinion on Therapeutic Targets” Blocking the prolactin receptor might help treat various diseases, but more research is needed.
38 citations
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April 2017 in “Journal of The American Academy of Dermatology” Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.
38 citations
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February 2006 in “British Journal of Clinical Pharmacology” The study found that combining different databases gives a better estimate of drug side effects in hospitals.
38 citations
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February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
37 citations
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December 2024 in “Theranostics” The hydrogel effectively treats infected burn wounds by reducing pain and preventing infection.
37 citations
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June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
37 citations
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April 2019 in “Journal of The American Academy of Dermatology” Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.
37 citations
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December 2014 in “Journal of Biomedical Informatics” Researchers created LabeledIn, a detailed list of drug uses, showing the importance of human input in making such lists.
36 citations
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June 2017 in “Journal of Cutaneous Medicine and Surgery” The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.
36 citations
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September 2014 in “Paediatric drugs” More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.
34 citations
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August 2005 in “Dermatologic Clinics” Stress and emotional factors can worsen skin conditions by affecting the immune system.
33 citations
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April 2002 in “Journal of Cutaneous Medicine and Surgery” Eating disorders can cause skin problems that need treating the underlying condition for better health.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
31 citations
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November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
30 citations
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May 2019 in “Scientific Reports” Late pregnancy helps repair brain damage in rats due to the GABAergic system.
30 citations
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March 2001 in “Environmental Health Perspectives” Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
29 citations
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January 2021 in “Translational Psychiatry” The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.
29 citations
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May 1998 in “Bulletin of the American College of Nurse-Midwifery” The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
28 citations
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November 2017 in “Skin appendage disorders” The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.