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Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

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The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Vepdegestrant may become the first FDA-approved PROTAC degrader, marking a new era in drug development.

Whole hair strands can reliably measure gamma ray exposure using ESR techniques, but samples should be analyzed quickly or stored in liquid nitrogen.

Epristeride's metabolism in zebrafish helps improve doping detection methods.

KLHL24-mutant stem cells help understand skin and heart disease.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

SRD5A2 gene variations affect PTSD symptoms differently in males and females.

The PP2A-B55α protein is essential for brain and skin development in embryos.

The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.

Taking 5-ARI before prostate laser surgery may lead to more blood changes, longer surgery, and more urinary issues.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

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FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.

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A new mutation in the KRT86 gene causes monilethrix in a Han family.

Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.

A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.