September 2023 in “Journal of the American Academy of Dermatology” Low-dose oral naltrexone may help reduce inflammation in some scarring alopecia patients.
August 2023 in “Journal of The American Academy of Dermatology” New treatments for hair loss include low-dose pills, updated drugs, supplements, light therapy, plasma injections, and advanced hair transplant techniques.
Telogen effluvium is a hair loss condition that can be treated with medications like minoxidil.
May 2022 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil often improves hair loss, and early treatment of traction alopecia is effective but harder if delayed.
August 2022 in “International Journal of Dermatology” Low-dose oral and sublingual minoxidil seem safe for children with hair disorders.
20 citations
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December 1994 in “Fertility and sterility” Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
3 citations
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May 2022 in “Journal of The American Academy of Dermatology” The conclusion is that 24 weeks of low-dose oral minoxidil is safe for men with hair loss, with no significant changes in heart rate or blood pressure.
5 citations
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July 2020 in “PubMed” Both oral contraceptives reduced hirsutism in PCOS patients, but adding metformin showed no extra benefit.
36 citations
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July 1980 in “Journal of Toxicology and Environmental Health” High doses of ethynylestradiol in rats caused growth issues, organ changes, and some tumors, but didn't increase overall tumor rates.
24 citations
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July 1980 in “Journal of Toxicology and Environmental Health” High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
May 2023 in “JAMA network open” After a New York Times article talked about using low-dose oral minoxidil for hair loss, more people started getting this drug prescribed, but this trend didn't last long.
September 2023 in “Food and chemical toxicology” High doses of some selenium supplements caused liver and reproductive harm in rats.
December 2024 in “Journal of Cosmetic Dermatology” Oral minoxidil rarely causes pericardial effusion, especially at low doses.
January 2023 in “Revista Eletrônica Acervo Saúde” Oral Minoxidil effectively treats hair loss with increased hair growth as a side effect, and low doses are generally safe.
January 2017 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” Hibiscus rosa-sinensis leaf extract is safe for mice at tested doses.
12 citations
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June 2023 in “Journal of trace elements in medicine and biology” Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.
13 citations
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July 2019 in “Toxicology research” Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
October 2012 in “Semina. Ciências Agrárias” A Shi Tzu dog with high cortisol levels improved after increasing the dose of trilostane.
23 citations
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September 2016 in “BMC musculoskeletal disorders” Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.
September 2020 in “Journal of Education, Health and Sport” Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.
February 2026 in “Journal of Dermatological Treatment” CG2001 is safe and well-tolerated for treating hair loss, with fewer side effects than oral finasteride.
15 citations
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September 2021 in “Journal of Clinical Medicine” High-dose oral minoxidil in children can cause increased hair growth, especially on the face.
11 citations
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July 2018 in “AJGP” Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.
March 2025 in “International Journal of Trichology” Low-dose oral minoxidil is safe for the heart.
Low-dose oral minoxidil is effective and generally safe for treating hair loss in women.
169 citations
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August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
May 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
20 citations
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November 2015 in “International Journal of Gynecology & Obstetrics” Both contraceptive pill doses effectively reduced androgen levels in women with PCOS.
January 2017 in “Faculty of 1000 Research Ltd” Oral minoxidil significantly reduces hair shedding in women with chronic telogen effluvium.
53 citations
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August 2019 in “Journal of The American Academy of Dermatology” Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.