July 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Activin A speeds up ear hair cell differentiation, while Follistatin slows it down.
125 citations
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March 2017 in “Micromachines” Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
66 citations
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May 2002 in “The Plant Journal” The IRE gene is important for normal root hair growth in Arabidopsis plants.
56 citations
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July 2004 in “Mechanisms of Development” Pax9 is crucial for proper tongue surface development and preventing skin-like changes.
23 citations
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May 2023 in “Cell Proliferation” TGF-β and FGF pathways are crucial for skin development and regeneration.
18 citations
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August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
8 citations
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April 2017 in “Journal of Dermatological Science” Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
5 citations
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December 2018 in “Frontiers in Endocrinology” Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
FoxA is crucial for pharynx regeneration in planarian flatworms.
1 citations
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September 2022 in “Journal of dermatological science” Certain vitamins and their derivatives can help hair grow longer by activating specific growth signals.
1 citations
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July 2021 in “Organoid (Online)” Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.
January 2026 in “Non-coding RNA Research” Exosomal miRNA-218-5p promotes hair growth and development.
August 2025 in “Current Issues in Molecular Biology” Key pathways like WNT, EGF, FGF, SHH, and BMP regulate poultry feather growth, with BMP inhibiting it.
Understanding hair follicle communication can help treat hair loss.
176 citations
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June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
105 citations
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October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
45 citations
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October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.
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February 2023 in “British Journal of Pharmacology” Isoxazole 9 (ISX9) may help regrow hair by activating certain cell signals.
3 citations
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April 2022 in “Bioengineering” Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
January 2026 in “Industrial Crops and Products” Ginsenoside Rf from Panax ginseng promotes hair growth and could be a natural alternative for treating hair loss.
April 2016 in “Journal of Investigative Dermatology” Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.
338 citations
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July 2009 in “Development” Sox2-positive cells determine specific hair follicle types in mammals.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
71 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
65 citations
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December 2000 in “PubMed” The biology of skin and hair is complex and not fully understood.
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March 2021 in “Experimental and Therapeutic Medicine” Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
10 citations
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May 2024 in “BioEssays” TRPV3 is important for skin health and could be a target for treating skin diseases.
7 citations
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April 2024 in “Life Medicine” Standardizing and engineering organoids can improve their use in medicine and drug testing.
4 citations
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July 2025 in “Organoids” Organoids can revolutionize medicine by modeling diseases and aiding in personalized treatments.
1 citations
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March 2019 in “International Journal of Molecular Medicine” Mouse hair follicle cells can become heart-like cells without genetic changes.