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11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro

research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro

7 citations , April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology”

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Tattoos: A Summary Knowledge for the Practicing Clinician

research Tattoos: A summary knowledge for the practising clinician

7 citations , August 2018 in “South African Medical Journal”

Clinicians should understand tattoos to manage health issues, as tattoos can cause complications and affect medical assessments.

research Core-shell nanocarriers based on PEGylated hydrophobic hyperbranched polyesters

7 citations , May 2016 in “European Polymer Journal”

The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.

research Fractal geometry and topology abstracted from hair fibers

7 citations , August 2009 in “Applied Mathematics and Mechanics-English Edition”

Hair fibers have fractal patterns with properties related to the golden mean, which may affect their functionality.

Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride

research Pharmacokinetic-pharmacodynamic modeling approach for dose prediction of the optimal long-acting injectable formulation of finasteride

6 citations , March 2021 in “International Journal of Pharmaceutics”

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

In Silico Analysis of Gene Expression Data from Bald Frontal and Haired Occipital Scalp to Identify Candidate Genes in Male Androgenetic Alopecia

research In silico analysis of gene expression data from bald frontal and haired occipital scalp to identify candidate genes in male androgenetic alopecia

6 citations , September 2019 in “Archives of Dermatological Research”

Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.

research Development of finasteride polymer microspheres for systemic application in androgenic alopecia

6 citations , March 2019 in “International Journal of Molecular Medicine”

Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.

Indian Gooseberry (Emblica Officinalis Gaertn.) Pharmacological Properties

research Indian Gooseberry (Emblica officinalisGaertn.)

6 citations , October 2017

Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.

Optimization of Microstructured Biodegradable Finasteride Formulation for Depot Parenteral Application

research Optimisation of microstructured biodegradable finasteride formulation for depot parenteral application

6 citations , February 2016 in “Journal of Microencapsulation”

Improved finasteride formula allows slow, sustained release and better absorption for patients.

research Cyclohex-1-ene Carboxylic Acids: Synthesis and Biological Evaluation of Novel Inhibitors of Human 5α Reductase

6 citations , March 2003 in “Archiv Der Pharmazie”

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Determination of Finasteride and Its Metabolite in Urine by Dispersive Liquid-Liquid Microextraction Combined with Field-Enhanced Sample Stacking and Sweeping

research Determination of finasteride and its metabolite in urine by dispersive liquid–liquid microextraction combined with field-enhanced sample stacking and sweeping

6 citations , March 2018 in “Journal of Chromatography A”

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

Simultaneous Determination of 30 Hormones Illegally Added to Anti-Aging Functional Foods Using UPLC-MS/MS Coupled with SPE Clean-Up

research Simultaneous determination of 30 hormones illegally added to anti-ageing functional foods using UPLC-MS/MS coupled with SPE clean-up

6 citations , September 2014 in “Food Additives & Contaminants: Part A”

New method effectively detects illegal hormones in anti-aging foods.

research Differential impact of environmental factors on systemic and localized autoimmunity

5 citations , May 2023 in “Frontiers in immunology”

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

research Nanoparticles in Cancer Treatment: A Narrative Review

5 citations , January 2022 in “Proceedings of the Pakistan Academy of Sciences B Life and Environmental Sciences”

Nanoparticles improve cancer treatment by reducing side effects and targeting cancer cells better.

Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme

research Theoretical evaluation of interaction of some dibenzo derivatives on both androgen receptor and 5α-reductase enzyme

5 citations , January 2022 in “Clinical cancer investigation journal”

Certain Dibenzo derivatives may help treat prostate cancer.

GC-MS Profiling and In Silico Prediction of MAPK Receptor Activation by Fatty Acids of Watercress Oil for Hair Growth Marketed in Saudi Arabia

research GC–MS profiling and in silico prediction of MAPK receptor activation by fatty acids of watercress oil for hair growth marketed in Saudi Arabia

5 citations , January 2021 in “Journal of Saudi Chemical Society”

Watercress oil may promote hair growth by activating specific receptors.

Characteristics And Alopecia Activity Of Pakis Gajah (Angiopteris Evecta) Growing In Galunggung Mountainside, West Java

research CHARACTERISTICS AND ALOPECIA ACTIVITY OF PAKIS GAJAH (ANGIOPTERIS EVECTA (G.FORST) HOFFM.) GROWING IN GALUNGGUNG MOUNTAINSIDE, WEST JAVA

5 citations , November 2017 in “Asian journal of pharmaceutical and clinical research”

Pakis Gajah (Angiopteris evecta) water extract may promote hair growth in rabbits, but more research is needed for human use.

research Hair Follicle Targeting with Nanoparticles

5 citations , September 2012 in “Springer eBooks”

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.