46 citations
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February 1983 in “The Journal of Dermatology” Hair regrowth slows with age due to changes in enzyme activity.
43 citations
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July 2012 in “Molecular human reproduction” Certain metabolites are lower in women with PCOS and could be potential markers for the condition.
42 citations
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February 1996 in “Journal of Investigative Dermatology” Polyamines, especially spermidine, are essential for hair growth.
37 citations
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January 2006 in “Carcinogenesis” Antizyme slows skin tumor growth by reducing cell growth in mice.
30 citations
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July 2010 in “Experimental Dermatology” Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
26 citations
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June 2003 in “PubMed” Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
14 citations
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March 2010 in “Gynecological endocrinology” New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
11 citations
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October 2005 in “Toxicological Sciences” Cigarette smoke condensates increase tumor-promoting markers in mouse skin, especially around hair follicles.
10 citations
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August 2013 in “Experimental Dermatology” Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
10 citations
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July 1980 in “British Journal of Dermatology” Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.
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August 2014 in “Biochemical and Biophysical Research Communications” ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.
6 citations
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November 2001 in “Der Hautarzt” Photothermolysis is the best method for permanent hair removal.
5 citations
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October 2013 in “Experimental Dermatology” The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.
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June 2009 in “The journal of alternative and complementary medicine/Journal of alternative and complementary medicine” Green tea extract may help reduce excessive hair growth.
1 citations
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August 2023 in “Andrology” Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.
1 citations
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April 2012 in “Cancer Research” Antizyme reduces tumor growth and normalizes skin cell development affected by MEK.
1 citations
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January 2009 in “Elsevier eBooks” Using Eflornithine cream with laser treatments improves facial hair removal.
Arginine deficiency hinders hair growth in androgenetic alopecia, but restoring it can promote hair regeneration.
January 2017 in “Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods” The supplement reduces hair loss and increases hair thickness in older women.
May 2024 in “The journal of sexual medicine” Finasteride treatment may cause erectile dysfunction, but stopping it reverses these effects.
May 2005 in “Molecular Carcinogenesis” mrp/plf-mRNA can indicate tumor-promoting effects in skin.
Suppressing ODC activity reduces tumor growth in hair follicles.
Introducing the OTC gene improved symptoms in mice with OTC deficiency.
31 citations
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September 2006 in “International journal of gynaecology and obstetrics” New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.
Problems with arginine processing in hair follicles might contribute to common hair loss, and arginine supplements could help treat it.
4 citations
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January 2011 in “International Journal of Trichology” Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.
April 2025 in “Experimental Eye Research” The Oat mouse model shows mild retinal degeneration, useful for testing treatments.
1 citations
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April 2021 in “Journal of Cosmetic Dermatology” The cream effectively reduced hair growth on forearms.
April 2026 in “Amino Acids” Polyamines are crucial for skin tumor development, and inhibiting them can prevent tumors.
77 citations
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January 1980 in “Carcinogenesis” TPA is about 50 times more effective at promoting tumors than MZ.