4 citations
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April 1989 in “The Journal of Dermatology” Trichohyalin granules help inner root sheath cells in hair follicles harden by integrating with keratin filaments.
62 citations
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October 2018 in “Journal of pathology” Keratin 17 is linked to various diseases, including cancer and skin conditions, and may be a target for diagnosis and treatment.
41 citations
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May 2020 in “Frontiers in immunology” Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
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March 1997 in “Research in Veterinary Science/Research in veterinary science” Epithelial proliferation and hyperkeratosis are linked to gastric ulcers in pigs.
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February 2015 in “Cell Death and Disease” Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
November 2025 in “Journal of Investigative Dermatology” 375 citations
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June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
149 citations
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July 2000 in “Molecular and Cellular Biology” Keratin 6a is important for quick wound healing from hair follicles.
211 citations
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April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
13 citations
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August 1985 in “The Journal of Dermatology” HKN-2 antibody targets specific skin and hair cells, showing keratin complexity.
128 citations
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February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
272 citations
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September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
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April 2012 in “Journal of Oral Pathology and Medicine” Rushton's hyaline bodies form from hair keratin and blood substances.
July 2023 in “Clinical Cosmetic and Investigational Dermatology” Accurate diagnosis of granular parakeratosis is crucial for effective treatment and improvement.
28 citations
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November 1987 in “Journal of the American Academy of Dermatology” The model successfully grew and differentiated hair follicle cells in the lab.
The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.
31 citations
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February 2007 in “Journal of Structural Biology” Oxidation changes the structure of hair protein filaments, causing them to compact and rearrange.
5 citations
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January 1981 Keratin proteins in hair are complex and come from multiple gene families.
23 citations
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February 2004 in “British Journal of Dermatology” Keratin in mouse hair follicles is complex and plays specific roles.
December 2000 in “日本組織細胞化学会総会プログラムおよび抄録集”
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January 2014 in “Cell structure and function” Different combinations of human hair keratins affect how hair fibers form.
May 2006 in “The Journal of Cell Biology” Keratin 17 is crucial for cell growth in wound healing by aiding protein synthesis.
The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.
February 1990 in “PubMed” Hair follicle cells and skin cells differ in keratinization and other features.
4 citations
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December 2013 in “The Journal of Dermatology” A new mutation in the K6b gene caused a girl's late-appearing nail condition.
September 2015 in “Italian Journal of Anatomy and Embryology” Human skin cells can be turned into heart cells.
7 citations
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October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
March 2023 in “International journal of integrated medical research” Keratosis pilaris is a common skin condition where hair follicles get clogged with keratin, mostly on the arms and thighs.
75 citations
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September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.