272 citations
,
September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
5 citations
,
December 1996 in “Biochemical and Biophysical Research Communications” Mouse hair keratins mHa1 and mHb4 can't form a strong network on their own in cells.
25 citations
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August 1991 in “Journal of Investigative Dermatology” 38 citations
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October 2001 in “British Journal of Dermatology” Keratin K6irs is a marker for the inner root sheath of hair follicles in mice and humans.
238 citations
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October 1994 in “Current opinion in genetics & development” The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.
2 citations
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August 2013 in “Journal of Investigative Dermatology” Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
34 citations
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June 1992 in “Journal of Cutaneous Pathology” Harlequin ichthyosis involves abnormal skin cell structures and giant mitochondria, affecting skin and hair.
Giant axonal neuropathy changes the structure of keratin in human hair, making it stiffer and stronger.
7 citations
,
January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry” April 2009 in “The FASEB Journal” Keratin biomaterials from human hair help nerve regeneration by activating Schwann cells.
149 citations
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July 2000 in “Molecular and Cellular Biology” Keratin 6a is important for quick wound healing from hair follicles.
46 citations
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December 1998 in “Journal of Biological Chemistry” Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.
9 citations
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July 2008 in “Archives of Dermatological Research” 13 citations
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August 1985 in “The Journal of Dermatology” HKN-2 antibody targets specific skin and hair cells, showing keratin complexity.
26 citations
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May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
31 citations
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January 2004 in “Methods in cell biology” Hair and follicle keratins differ in structure and expression, especially in cysteine content.
16 citations
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January 2018 in “Advances in experimental medicine and biology” Hair and wool have diverse keratins and keratin-associated proteins.
161 citations
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June 1993 in “Journal of Biological Chemistry” Trichohyalin helps in hair and skin cell structure and function by binding calcium and linking proteins.
63 citations
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December 1998 in “Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology” The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.
42 citations
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July 2015 in “PLoS ONE” The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.
122 citations
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June 2002 in “Genes & Development” Keratin 17 is crucial for early hair strength and cell survival.
December 2022 in “Communications biology” 10 citations
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January 2010 in “International journal of trichology” Keratin-associated proteins are part of the developing hair fiber cuticle.
August 1993 in “Journal of Dermatological Science” 482 citations
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June 1979 in “Proceedings of the National Academy of Sciences” Keratins provide structural strength in epithelial cells and help identify cell origins.
93 citations
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July 2006 in “Journal of Investigative Dermatology” K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.
75 citations
,
September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
88 citations
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March 2004 in “Journal of Investigative Dermatology”
Brazilian keratin treatment can cause skin reactions like eczema.
248 citations
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April 1988 in “Differentiation” Human and bovine hair follicles have distinct cytokeratins specific to hair-forming cells.