research The Art of Building Living Tissues: Exploring the Frontiers of Biofabrication with 3D Bioprinting
3D bioprinting is advancing rapidly, improving regenerative therapy and drug delivery.
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research BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin
Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
research Estrone Sulfate Source of Estrone and Estradiol Formation in Isolated Human Hair Roots: Identification of a Pathway Linked to Hair Growth Phase and Subject to Site-, Gender-, and Age-Related Modulations
Estrogen formation in hair roots affects hair growth and varies by site, gender, and age.
research Expression of mineralized tissue associated proteins: Dentin sialoprotein and phosphophoryn in rodent hair follicles
Dentin sialoprotein and phosphophoryn are present in rodent hair follicles and may help hair growth and development.
research 피부장벽, 이온, 사이토카인
Calcium is crucial for skin development and healing.
research Review Use of Tisseel, a Fibrin Sealant, for Particulate Graft Stabilization
Tisseel shows promise for bone graft stabilization but needs more clinical trials to confirm its effectiveness.
research A mechanism for topical cutaneous calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
research Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs
Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.
research TERMIS ‐ AMERICAS Toronto, Ontario, Canada July 10–13, 2022
Advancements in skin treatment and wound healing include promising gene therapy, 3D skin models, and potential new therapies.
research De novo follicular regeneration of the skin by wingless int 3 and bone morphogenetic protein 2 genes introduced into dermal fibroblasts and fibroblast growth factor‐2 protein
Genetically modified cells can regenerate skin and hair in rats.
research Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding
research Scalable biofabrication and morphology evaluation of tissue spheroids
research LB1774 Establishing competent morphogenetic fields for tissue pattern regeneration in skin organoids
Skin organoids can regenerate hair by forming specific cell units with certain signals.
research Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor
Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
research Ear pinna growth and differentiation is conserved in murids and requires BMP signaling for chondrocyte proliferation
BMP5 is essential for ear cartilage cell growth in rodents.
research Factors affecting bone maturation in Chinese girls aged 4-8 years with isolated premature thelarche
Obesity and certain hormone levels can lead to advanced bone age in young girls with early breast development.
research Skin tissue engineering
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes
Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
research The effect of 1,25-dihydroxyvitamin D3 on the growth and differentiation of cultured human outer root sheath cells from normal subjects and patients with vitamin D-dependent rickets type II with alopecia
research Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device
Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.
research Cultivation of Murine Hair Follicles as Organoids in a Collagen Matrix
research Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
research IGF1- and BM-MSC-incorporating collagen-chitosan scaffolds promote wound healing and hair follicle regeneration.
Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.
research Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1
Male cells need DHT to respond to testosterone, while female cells do not.
research Building a Better Scar: Re-engineering Extracellular Matrix Structure in Dermal Scars
αCT1 improves scar appearance by changing early collagen structure.
research Electrospun 3D nanofibrous materials and their applications in orthopaedics
Electrospun 3D nanofibrous materials show promise for bone regeneration in orthopaedics.
research Assessment of replication rates of human keratinocytes in engineered skin substitutes grafted to athymic mice
Regulating keratinocyte growth in engineered skin can improve wound healing.
research Dynamic expression of Runx1 in skin affects hair structure
Runx1 is crucial for proper hair structure and development.
research Stroke Recovery
Transplanted human Olig2+ astroglia may help improve learning and memory after a stroke.
research Expression of Wnt Genes in Echinaster Sepositus Arm Regeneration
Wnt genes help starfish regrow arms by aiding wound healing and cell development.