20 citations
,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
2 citations
,
January 2018 in “Biology and medicine” High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
May 2023 in “International Journal of Home Science” PCOS is linked to metabolic issues and infertility, needing more research.
January 2021 in “Journal of Scientific Research of the Banaras Hindu University” Lifestyle changes and medical treatment can help manage PCOS symptoms in young adults.
30 citations
,
March 2010 in “European Journal of Dermatology” Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.
1 citations
,
December 1997 in “Journal of The European Academy of Dermatology and Venereology” All women with significant unwanted hair growth have hormonal imbalances, often from polycystic ovary syndrome.
393 citations
,
November 2000 in “Archives of General Psychiatry” Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
165 citations
,
February 1994 in “Fertility and Sterility” Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.
98 citations
,
February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
68 citations
,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
57 citations
,
August 1995 in “British Journal of Dermatology” Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
56 citations
,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
51 citations
,
September 2015 in “Medical Clinics of North America” The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.
47 citations
,
November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
46 citations
,
November 1997 in “Journal of Neural Transmission” Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
45 citations
,
February 2001 in “Joint bone spine” Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
45 citations
,
September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
40 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
30 citations
,
December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
22 citations
,
April 2015 in “Current problems in dermatology” Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
21 citations
,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
19 citations
,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
16 citations
,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
11 citations
,
September 2011 in “British Journal of Dermatology” New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.
11 citations
,
January 2011 in “Indian Dermatology Online Journal” Eating dairy and high glycemic foods may increase the risk of acne.
7 citations
,
April 2015 in “General and Comparative Endocrinology” Finasteride negatively affects fish reproduction and gonadal development.
5 citations
,
January 2020 in “in Vivo” Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
4 citations
,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
1 citations
,
September 2016 in “British Journal of Dermatology” Women with aging signs and heart issues have higher hair loss risk, which may predict shorter lifespan and affect attractiveness.
1 citations
,
September 2023 in “Journal of Education Health and Sport” Anabolic-androgenic steroids are dangerous and educating people about their risks is essential.