34 citations
,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.
9 citations
,
January 2022 in “Reproductive Biology and Endocrinology” High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
437 citations
,
August 2014 in “Cell metabolism” Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.
2 citations
,
February 2021 in “Endocrinology, diabetes & metabolism case reports” A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.
92 citations
,
May 2014 in “The American Journal of Medicine” The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.
September 2008 in “Fertility and Sterility” Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
June 2025 in “Research Square (Research Square)” HAIR-AN syndrome mainly affects obese women and can be improved with early diagnosis and treatment using insulin-sensitizing agents.
5 citations
,
October 2018 in “Medical Science Monitor” Women with PCOS have lower amylin levels, which are not related to their body weight.
25 citations
,
September 2024 in “Cardiovascular Drugs and Therapy” GLP1-RAs may have higher reports of suicidal events and hair loss compared to other diabetes drugs.
October 2024 in “Journal of the Endocrine Society” The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.
November 2022 in “International Journal of General Medicine” Women with Polycystic Ovary Syndrome are more likely to have Non-Alcoholic Fatty Pancreas Disease, which is associated with older age, metabolic syndrome, insulin resistance, and high male hormone levels.
53 citations
,
April 2016 in “PubMed” PCOS affects multiple organs and requires combined treatment with lifestyle changes, metformin, and oral contraceptives.
December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)” AKR1C3 could be a treatment target for metabolic issues in PCOS.
3 citations
,
August 1992 in “Bulletin of Experimental Biology and Medicine” Diabetes changes keratin in skin and hair, affecting their health.
222 citations
,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
3 citations
,
May 2023 in “Endocrine Abstracts” PCOS has three subtypes, with 11-oxygenated androgens increasing metabolic risk.
1 citations
,
July 2025 in “Middle East Fertility Society Journal” Autoimmune markers may help diagnose and manage PCOS.
4 citations
,
June 2019 in “Revista brasileira de ginecologia e obstetrícia” Using only hyperandrogenism to diagnose PCOS can lead to overdiagnosis.
4 citations
,
September 2025 in “Biomolecules” The effect of GLP-1 RAs on erectile function is unclear and needs more research.
October 2023 in “Journal of the Endocrine Society” Losing weight, possibly through bariatric surgery, is key to improving PCOS and hyperandrogenism symptoms in obese patients.
September 2015 in “Turkish Journal of Endocrinology and Metabolism” Consider Werner syndrome in young patients with early aging signs and metabolic issues.
2 citations
,
January 2025 in “touchREVIEWS in Endocrinology” SGLT2 inhibitors may help manage PCOS symptoms effectively.
5 citations
,
October 1988 in “Diabetes Research and Clinical Practice” Hair glycation can indicate long-term blood sugar trends in diabetics.
4 citations
,
September 2023 in “Nutrients” Managing diabetes can lead to eating disorders, and eating disorders can make diabetes harder to control.
July 2025 in “International Journal of Dermatology”
2 citations
,
May 1999 in “PubMed” Hyperandrogenism in women can cause acne, hair growth, hair loss, irregular periods, and increase the risk of infertility and diabetes.
October 2025 in “Indian Journal of Physiology and Pharmacology” Early diagnosis and treatment of endocrine disorders like HAIR-AN syndrome can improve outcomes in adolescents.
104 citations
,
June 2020 in “Journal of Endocrinology” Hyperandrogenism and insulin resistance in PCOS-like rats can lead to pregnancy complications due to increased cell death in the uterus and placenta.
October 2010 in “Reproductive Biomedicine Online” Women with PCOS and androgenic alopecia have different triglyceride metabolism compared to those without hair loss.
June 2026 in “Dermatology and Therapy” GLP-1RAs, like semaglutide and tirzepatide, may cause hair loss, so patients should be informed and monitored.