January 2007 in “UNIFESP Institutional Repository (Universidade Federal de São Paulo)” Addressing anxiety and mood disorders is crucial to reduce medication overuse in chronic migraine patients.
26 citations
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January 2004 in “Journal of Toxicology Clinical Toxicology” Accidentally eating autumn crocus can cause long-term health issues.
November 2015 in “Clin-Alert” Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
January 1994 in “Toxicological Sciences” Lower dosages of 2-(difluoromethyl)-dl-ornithine might reduce side effects, supporting further research.
May 2024 in “IntechOpen eBooks” More oxygen isn't always better and can sometimes be worse.
February 2020 in “Scholars academic journal of pharmacy” The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.
November 2001 in “The Journal of neuropsychiatry and clinical neurosciences/The journal of neuropsychiatry and clinical neurosciences” Divalproex sodium can unexpectedly cause agitation and hyperactivity in some patients.
November 2005 in “PubMed” 8 citations
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July 2003 in “Journal of the American Geriatrics Society” Venlafaxine may cause paranoid delusions in some patients.
January 2026 in “JCEM Case Reports” A woman with hypothyroidism developed an allergy to IV levothyroxine after being resistant to oral forms.
15 citations
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May 2003 in “Choice Reviews Online”
14 citations
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June 1952 in “The BMJ” Phenobarbitone can cause severe and sometimes fatal skin reactions.
February 2012 in “Hospital Pharmacy” Doxycycline or flucloxacillin can cause a rare, severe skin reaction that can be fatal, especially in the elderly.
5 citations
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November 2012 in “Journal of Clinical Psychopharmacology” Valproic acid and isoniazid can interact, causing toxicity, so careful monitoring is needed.
October 2025 in “The American Journal of Gastroenterology” Excessive zinc intake can cause liver failure.
May 2018 in “Dermatologic Surgery” October 2025 in “Journal of the Endocrine Society” Careful dosing and monitoring are crucial to prevent adrenal insufficiency when using ketoconazole for Cushing's disease.
2 citations
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January 2015 in “Journal of Investigative Dermatology” 14 citations
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December 2017 in “Journal of Intensive Care” Lithium poisoning can cause severe health complications and requires careful monitoring.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
21 citations
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August 2002 in “British Journal of Ophthalmology” Drug misuse can cause serious eye infections and other severe side effects.
14 citations
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June 2009 in “Journal of veterinary internal medicine” High doses of albendazole can be deadly for alpacas.
August 2013 in “Hospital Pharmacy” Certain medications can cause serious side effects, including skin reactions, stroke, muscle disorders, tongue swelling, hair loss in women, and liver failure.
21 citations
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February 2021 in “BMJ case reports” Anabolic steroid users may face higher risk of severe COVID-19.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
15 citations
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September 2021 in “Journal of Clinical Medicine” High-dose oral minoxidil in children can cause increased hair growth, especially on the face.
44 citations
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September 1948 in “Radiology” Too much vitamin A can cause serious health problems.
26 citations
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January 2018 in “Skin appendage disorders” Thallium, mercury, selenium, and colchicine strongly cause hair loss.
2 citations
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March 2022 in “Laboratory Animal Research” A mild botulinum toxin injection improved sperm production and movement in aging mice.