79 citations
,
January 1975 in “Food and Cosmetics Toxicology” The hair dye formulations tested did not cause long-term toxicity or cancer in mice.
3 citations
,
January 2013 in “Journal of cosmetics, dermatological sciences and applications” HAIRCARECUBE TM (HCC) helps hair products work better by getting active ingredients deeper into the hair.
4 citations
,
November 2022 in “Journal of biomedical materials research. Part B, Applied biomaterials” Human hair proteins, especially keratins, can protect cells from oxidative stress in lab settings.
November 2016 in “University of the Arts London Research Online (University of the Arts London)” Shampoos with polymers and dyes help maintain and enhance hair color vibrancy.
1 citations
,
June 2023 in “Skin Research and Technology” Hair-coating shampoos dye better initially, but hair-oxidation shampoos keep color longer and may damage hair more.
16 citations
,
October 2009 in “Xenobiotica” The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” A new hair dye method uses polyphenols and oxidation to create a long-lasting brown color on gray hair.
December 2025 in “Biomedicine & Pharmacotherapy” Melamax® protects skin from UV damage and reduces inflammation and oxidative stress.
June 2026 in “Applied and Computational Engineering” The document reviews the principles of hair dye, categorizing them into oxidative and non-oxidative dyes, with non-oxidative dyes further divided into temporary and semi-permanent types. By analyzing these principles, the study aims to improve the quality and safety of hair dyes, making the dyeing process safer and more convenient. The review highlights significant differences in the duration, application methods, and potential risks associated with each type of dye, suggesting that understanding these differences can lead to better and safer hair dye products.
66 citations
,
February 1985 in “Archives of dermatological research” Hair dyes penetrate the scalp very minimally, less than 1%.
March 2025 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study investigated the protective effects of antioxidants, specifically ferulic acid and resveratrol, on chemically damaged hair. Using standardized bleached Caucasian hair strands, the research involved two stages: treatment with oxidative hair dye containing antioxidants and application of leave-in conditioners with antioxidants followed by simulated solar exposure. The results showed that both antioxidants effectively protected hair fibers, increasing denaturation energy by up to 35% and reducing protein loss compared to untreated hair. While they did not prevent cysteine oxidation during dyeing, they significantly reduced cysteine oxidation by about 50% during solar exposure. The study concludes that incorporating ferulic acid or resveratrol in cosmetic formulations effectively protects hair from oxidative damage caused by chemical processes and sun exposure.
215 citations
,
March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
81 citations
,
November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
43 citations
,
August 2016 in “International Journal of Nanomedicine” Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
40 citations
,
February 2002 in “International Journal of Dermatology” Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.
11 citations
,
August 2015 in “PLOS ONE” Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.
6 citations
,
December 2018 in “Medical principles and practice” Using hair dye may slightly increase the risk of non-Hodgkin's lymphoma, especially with long-term use.
3 citations
,
May 2020 in “Annals of the Academy of Medicine Singapore” Hair dye can cause serious scalp issues, including skull erosion.
1 citations
,
October 2013 in “Our Dermatology Online” 5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.
9 citations
,
January 2010 The herbal hair dye is a safe and eco-friendly alternative to conventional dyes.
19 citations
,
January 2012 in “Annals of Dermatology” People need more information about hair dye ingredients and side effects.
5 citations
,
June 2013 in “Fashion business” Rosehip extract improves hair wave, thickness, and color vibrancy.
1 citations
,
July 2022 in “Han'gug sigpum yeong'yang gwahag hoeji/Journal of the Korean society of food science and nutrition” Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.
18 citations
,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
January 2025 in “International Journal of Advanced Research in Science Communication and Technology” Polyherbal hair dyes are safer and more eco-friendly than chemical dyes.
March 2025 in “International Journal of Advanced Research in Science Communication and Technology” Herbal hair dyes are safer and eco-friendly alternatives to synthetic dyes, offering natural color and hair benefits.
40 citations
,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
4 citations
,
January 2018 in “Urology & Nephrology Open Access Journal” Hair dye chemicals can cause serious health problems, including kidney damage.
5 citations
,
April 2018 in “Chem” Graphene-based hair dye is a safe, durable, and effective alternative to traditional black hair dyes.
3 citations
,
January 2007 in “Journal of health science” The enzymatic method can effectively identify chemical treatments on hair.