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The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

pCLCA2 protein may help maintain skin structure and function.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.

CCCA may involve the PD1/PDL1 pathway and increased caspase 3, leading to permanent hair loss.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.

A patient with total hair loss developed vitiligo after using a treatment called DCP.

The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.

The new cocrystal KET-PABA is a more effective and safe anti-inflammatory treatment for skin conditions in mice.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

TACE/ADAM17 is essential for maintaining healthy hair and hair follicle stem cells.

Aromatase gene variation may increase female hair loss risk.

The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.

People with the same genetic mutation for Woodhouse-Sakati syndrome can have different symptoms.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

A mouse gene mutation increases the risk of skin cancer.

The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.

Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.