research Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
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810-840 / 1000+ results research Hedgehog Pathway Inhibitors against Tumor Microenvironment
Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.
research Comparison of prevalence of periodontal disease in women with polycystic ovary syndrome and healthy controls
Women with PCOS may be more likely to have gum disease than healthy women.
research The Effect of Nanoparticle-Incorporated Natural-Based Biomaterials towards Cells on Activated Pathways: A Systematic Review
Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.
research Delivery systems in nanocosmeceuticals
Nanoparticles can make cosmetics more effective but have challenges like cost and safety.
research Epidermal stem cells: skin surveillance and clinical perspective
Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
research Advances in polymeric nano-delivery systems targeting hair follicles for the treatment of acne
Polymer-based nanocarriers can improve acne treatment by delivering drugs through hair follicles more effectively.
research Medicinal value of hibiscus rosa sinensis : a review
Hibiscus rosa sinensis, especially the red variety, has significant medicinal properties and is used in pharmaceuticals.
research Anti-Müllerian Hormone and Polycystic Ovary Syndrome in Women and Its Male Equivalent
High AMH levels are linked to PCOS in women and may have a male equivalent with similar traits.
research β1 Integrins with Individually Disrupted Cytoplasmic NPxY Motifs Are Embryonic Lethal but Partially Active in the Epidermis
Mutations in β1 integrins cause embryonic death but have milder effects on skin.
research The treatment of polycystic ovary syndrome.
PCOS treatment focuses on inducing ovulation, reducing androgens, and managing long-term health risks with medications and lifestyle changes.
research Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Ferulic Acid Induces Keratin 6α via Inhibition of Nuclear β-Catenin Accumulation and Activation of Nrf2 in Wound-Induced Inflammation
Ferulic acid helps wounds heal faster by reducing inflammation and promoting skin cell movement.
research Skin Development and Disease: A Molecular Perspective
Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Building Fucoidan/Agarose-Based Hydrogels as a Platform for the Development of Therapeutic Approaches against Diabetes
Agarose/fucoidan hydrogels may help treat diabetes by supporting pancreatic cell growth.
research Physical and mechanical cues affecting biomaterial-mediated plasmid DNA delivery: insights into non-viral delivery systems
Biomaterials can improve non-viral gene delivery by enhancing DNA uptake and reducing toxicity.
research Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium
Stem cells in the eye have different roles and behaviors, helping maintain and repair the eye's surface.
research Emerging roles of Sox6 in the renal and cardiovascular system
Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.
research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
research Research Progress of Sodium Alginate-Based Hydrogels in Biomedical Engineering
Sodium alginate-based hydrogels are promising for medical use due to their versatility and biocompatibility.
research Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders
New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
research Saying no to SARS-CoV-2: the potential of nitric oxide in the treatment of COVID-19 pneumonia
Nitric oxide may help treat COVID-19 pneumonia by fighting the virus and easing symptoms.
research Skin-type-dependent development of murine mechanosensory neurons
Mechanosensory neurons adapt to different skin types after birth.
research The Pressurized Skin: A Review on the Pathological Effect of Mechanical Pressure on the Skin from the Cellular Perspective
Understanding how skin cells react to pressure can help diagnose and manage pressure-related skin disorders.
research A Full Factorial Design to Optimize Aminexil Nano Lipid Formulation to Improve Skin Permeation and Efficacy Against Alopecia
research Cell death in skin function, inflammation, and disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research The mechanical forces that shape our senses
Mechanical forces are crucial in shaping our sensory organs during development.
research Exploring the Potential of Mesenchymal Stem Cell–Derived Exosomes for the Treatment of Alopecia
Exosomes from stem cells might help treat hair loss.
research Gastroparesis - a novel cause of persistent thyroid stimulating hormone elevation in hypothyroidism.
Gastroparesis can cause persistent TSH elevation in hypothyroidism despite treatment.