Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
October 2025 in “Journal of the Endocrine Society” Ovarian hyperthecosis can cause high testosterone and symptoms like hair loss, and surgery can help improve these symptoms.
24 citations
,
March 2022 in “Frontiers in plant science” Plant root hair growth is mainly controlled by hormones like auxin and ethylene, which promote growth, while others like brassinosteroid inhibit it.
April 2020 in “Journal of the Endocrine Society” A rare ovarian tumor caused high male hormone levels, but surgery fixed it.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
1 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” Hypothyroidism may worsen metabolic problems like insulin resistance and obesity in women with PCOS.
26 citations
,
March 2018 in “Experimental Dermatology” Prolactin may influence skin glands and could be a target for treating acne and skin aging.
January 2024 in “International Journal of Health Science” Hormonal implants have many side effects that often outweigh their benefits.
26 citations
,
March 1981 in “Clinical Endocrinology” Oestrogen does not affect adrenal androgen levels in children and adolescents.
August 2023 in “Clinical and Experimental Dermatology” The document discusses a special exam case for formulating and using systemic therapy named Athena.
88 citations
,
July 2009 in “Experimental and Clinical Endocrinology & Diabetes”
97 citations
,
November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
61 citations
,
December 1994 in “Planta”
2 citations
,
November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
50 citations
,
February 2013 in “Annals of Clinical Biochemistry” Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
7 citations
,
April 1996 in “Archives of dermatological research” Topical tacalcitol can treat psoriasis by acting directly on skin cells.
June 1995 in “International Journal of Gynecology & Obstetrics” Cabergoline is more effective and has fewer side effects than bromocriptine for treating women with hyperprolactinemic amenorrhea.
23 citations
,
March 1998 in “BMJ” Haemochromatosis can cause infertility by affecting hormone glands.
December 2017 in “Elsevier eBooks” The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.
6 citations
,
January 1977 in “Archives of dermatological research” 96 citations
,
September 1975 in “The Journal of Clinical Endocrinology & Metabolism” Hormone levels change during puberty, leading to physical developments like pubic hair and voice changes.
13 citations
,
May 2007 in “Journal of Endocrinology” Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
15 citations
,
January 1995 in “Archives of dermatological research” OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.
22 citations
,
January 2008 in “Physiological Research” Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
5 citations
,
June 2015 in “International Journal of Women's Dermatology” Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.
8 citations
,
June 2016 in “Clinical Chemistry” PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
519 citations
,
February 2020 in “Inflammation and Regeneration” RANKL is crucial for bone health, immune function, and other body processes.
7 citations
,
April 2023 in “Biomedicines” Dihydrotestosterone boosts inflammation in fat cells more than testosterone.
26 citations
,
October 2002 in “Journal of Investigative Dermatology” A specific gene mutation causes congenital hair loss.
43 citations
,
May 1986 in “Clinics in Endocrinology and Metabolism” Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.