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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Cathepsin L is essential for normal hair growth and development.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Hair loss in men treated best with early medication or transplant, new treatments researched.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

The document concludes that proper diagnosis and evidence-based treatments are crucial for managing hair diseases, and psychological support for patients is important.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.