research Isolation and Molecular Cloning of Epidermal- and Hair Follicle-Specific Peptidylarginine Deiminase (Type III) from Rat
PAD type III enzyme is specific to rat skin and hair follicles.
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research A Fatty Acid / Protein Complex in Human Hair
A fatty acid/protein complex in human hair helps protect it from damage.
research Hair Follicle Proteoglycans.
research Author response: The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome
Defective protein folding due to a mutation is key in ANE syndrome.
research Distribution of acid and alkaline phosphatases in canine skin.
ALP and ACP have different roles in dog skin, with ALP aiding growth and maintenance, and ACP involved in breakdown processes.
research Characterization of nonkeratinous proteins extracted from human hair by permanet wave lotion.
Permanent wave lotion can extract proteins from hair, especially when pH is higher, and repeated treatments or bleaching can damage hair.
research Protease activity, localization and inhibition in the human hair follicle
The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.
research A Novel Serine Protease Overexpressed in the Hair Follicles of Nude Mice
A new enzyme, BSSP, is found in high amounts in the hair follicles of nude mice.
research A Combinatorial Tweet Clustering Methodology Utilizing Inter and Intra Cosine Similarity
The method effectively grouped tweets into categories without knowing the number of groups beforehand.
research TLR3 signaling modulates immunomodulatory property of human periodontal ligament stem cells.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
research Efficacy and safety evaluations of topical proretinal nanoparticles
Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
research Alopecia Areata
A 45-year-old woman with autoimmune diseases experienced patchy hair loss due to alopecia areata, which has no cure but can be treated, with varying success.
research Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase
A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
research 494 Epidermolysis bullosa pruriginosa, muscular dystrophy, and immune-mediated myasthenia gravis in a patient with homozygous nonsense PLEC mutation
A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.
research Interaction of polypeptides with hair in different reducing environments
Small KP peptide improves hair without reducing agents, while larger proteins need them for better results.
research 090 Reactive lipids from the secretome of senescent fibroblasts modify the extracellular matrix with functional consequences for resident cells
Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
research Granzyme B in skin aging, injury and repair
Granzyme B accelerates skin aging and impairs healing by breaking down important skin components.
research 1393 Human TMEM2 is not a hyaluronidase but a regulator of hyaluronan metabolism
Human TMEM2 does not break down hyaluronan but helps control its metabolism.
research Demonstrating the potential of untargeted hair proteomics for personalized biomarkers in stress-associated disorders
Hair proteomics could be a useful, non-invasive tool for identifying stress-related disorders.
research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
research Polymorphic Enzyme Systems in Human Hair Sheath Cells
Enzyme presence in hair sheath cells decreases over time, affecting forensic analysis.
research Development and evaluation of RADA-PDGF2 self-assembling peptide hydrogel for enhanced skin wound healing
RADA-PDGF2 hydrogel speeds up wound healing and is safe for use.
research A case of MBTPS1 ‐related disorder due to compound heterozygous variants in MBTPS1 gene: Genotype–phenotype expansion and the emergence of a novel syndrome
A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.
research Olink proteomics analysis of scalp psoriasis reveals a cytokine storm inflammatory mainly related to bacterial-derived antigens
Scalp psoriasis inflammation is mainly caused by bacteria-related triggers.
research Nano-PROTACs: state of the art and perspectives
Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
research Antioxidant and anticancer properties of bioactive peptides from Lablab purpureus
Lablab purpureus peptides may effectively kill cancer cells with fewer side effects.
research Identification and Characterisation of a Novel Pathogenic Mutation in the Human Lipodystrophy Gene AGPAT2
A new mutation in the AGPAT2 gene causes severe fat tissue loss and related health issues by reducing the protein's levels.
research Perturbations in fatty acid metabolism and collagen production infer pathogenicity of a novel MBTPS2 variant in Osteogenesis imperfecta
A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.
research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene
Researchers found a non-functional sheep keratin gene due to mutations.
research Demonstrating the potential of untargeted hair proteomics for personalized biomarkers in stress-associated disorders
Hair proteomics could be a promising non-invasive way to identify stress-related disorders.