January 2007 in “E-Deusto: conocimiento para ir por delante” The study provided insights into burn healing and scarring, aiding future treatment development.
July 2004 in “Journal of Clinical Oncology” Isolated hyperthermic chemotherapy perfusion for limb melanoma is safe and effective with manageable side effects.
January 2002 in “Agritrop (Cirad)” The hr gene is linked to hair loss in Valle del Belice sheep.
January 2000 in “The Journal of Trace Elements in Experimental Medicine” Zinc supplementation effectively treats acrodermatitis enteropathica symptoms.
354 citations
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February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
277 citations
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February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
269 citations
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May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
256 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
195 citations
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January 2008 in “Photochemistry and Photobiology” Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.
188 citations
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June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
180 citations
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January 2003 in “American Journal of Clinical Dermatology” Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
169 citations
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May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
144 citations
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December 2004 in “Molecular Endocrinology” The vitamin D receptor is essential for normal hair growth, even without its usual binding.
138 citations
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June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
138 citations
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May 2000 in “Maturitas” Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
104 citations
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January 2005 in “Climacteric” Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.
102 citations
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April 2014 in “International Journal of Dermatology” The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.
92 citations
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June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
88 citations
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August 2014 in “PLOS genetics” Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
85 citations
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May 2009 in “Hippocampus” Progesterone helps adult male mice grow more neurons and improves memory.
84 citations
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February 1981 in “Journal of Endocrinology” Epidermal growth factor slows hair and body growth in mice.
81 citations
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November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
81 citations
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March 1985 in “Journal of Clinical Investigation” Measuring 24-OHase induction helps identify defects in vitamin D processing and predict treatment response.
77 citations
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February 2001 in “Journal of Dermatological Science” HGF activator helps convert HGF to its active form, promoting hair growth.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
71 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
71 citations
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May 1996 in “Journal of Investigative Dermatology” Ornithine decarboxylase is crucial for hair growth regulation in mice.
68 citations
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May 2013 in “The American journal of medicine” Traditional Chinese medicines with heavy metals can cause severe poisoning.
66 citations
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July 2010 in “Journal of Proteome Research” Trichohyalin may trigger the immune response causing alopecia areata.
64 citations
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March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.