February 2026 in “Journal of Allergy and Clinical Immunology” Alopecia areata involves immune system issues and specific cell types that disrupt hair growth, leading to hair loss.
July 2019 in “Journal of Investigative Dermatology” The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
22 citations
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January 2013 in “International Journal of Trichology” Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.
6 citations
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January 2011 in “PubMed” The document concludes that most patients with endocrine disorders experience diffuse, non-scarring hair loss, with scarring hair loss being rare.
Chronic hair diseases can severely impact mental health and self-confidence.
December 2014 in “PubMed” A scalp biopsy can help confirm hair loss types when other methods don't provide a clear diagnosis.
3 citations
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April 2015 in “American journal of biomedical sciences” Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
3 citations
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May 2021 in “Dermatologic Clinics” The document concludes that more research is needed to understand hair loss in men and to find new treatments.
January 2012 in “Postgraduate obstetrics & gynecology” Up to half of women by age 50 experience significant hair loss, with various types and treatments available.
August 2025 in “Галицький медичний вісник” Understanding hair follicle changes and hormones is key to diagnosing and treating hair loss.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
4 citations
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December 2020 in “Journal of Dermatology” Impaired autophagy may cause hair loss by triggering early catagen.
101 citations
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January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
1 citations
,
October 2014 in “Paediatrics and Child Health” The document concludes that proper diagnosis and management of hair loss in children require a detailed examination and understanding of various hair disorders.
191 citations
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May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
April 2026 in “Academia Polonica.” Alopecia in women can signal broader health issues and requires a thorough diagnosis to tailor treatments.
April 2017 in “Journal of Investigative Dermatology” Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.
59 citations
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February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
1 citations
,
January 2021 in “Journal of V. N. Karazin Kharkiv National University: Series Medicine” Nonandrogenic factors like oxidative stress and microinflammation are important in hair loss progression.
148 citations
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September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.
May 2022 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Women's hair loss can be due to hormonal changes and various conditions, with treatments focusing on stopping progression and managing symptoms.
December 2025 in “International Journal of Dermatology and Venereology” Targeted immunotherapies may offer better treatment for alopecia areata by controlling inflammation and immune responses.
July 2022 in “Journal of Investigative Dermatology” Substance P may contribute to hair loss by increasing oxidative stress and mitochondrial activity in hair follicles.
February 2023 in “Cosmoderma” An infant with complete hair loss was diagnosed with a genetic disorder affecting hair growth.
January 2013 in “Digital Repository (National Repository of Grey Literature)” Hair loss negatively affects self-esteem and identity.
2 citations
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May 2018 in “Journal of The American Academy of Dermatology” Hypothyroidism patients with hair loss typically have thinning hair, smaller hair follicles, and normal hair shedding.
52 citations
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April 2004 in “Journal of The American Academy of Dermatology” Male pattern baldness involves three mechanisms and finasteride can help reverse it.
January 2008 in “Journal of Practical Dermatology”
June 2023 in “Research Square (Research Square)” Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
21 citations
,
October 2009 in “Molecular Biology Reports”