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Chromatin Remodeler Lymphoid-Specific Helicase (Lsh) Is a Critical Determinant Controlling Postnatal Epidermal Growth, Differentiation, and Response to Injury

research 707 Chromatin remodeler Lymphoid-specific helicase (Lsh) is a critical determinant controlling postnatal epidermal growth, differentiation and response to injury

April 2016 in “Journal of Investigative Dermatology”

Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.

research Pure Hair‐Nail Ectodermal Dysplasia: Expanding the HOXC13 Genotypic Spectrum

February 2026 in “Pediatric Dermatology”

research 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing

July 2024 in “Journal of Investigative Dermatology”

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

research Synchronizing actin and microtubules for axonal branching

3 citations , August 2012 in “Nature Cell Biology”

Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.

Follistatin and Secreted Frizzled-Related Protein 1, OVOL1-Regulated Genes, Are Important for Hair Follicle Neogenesis

research Follistatin and secreted frizzled-related protein 1, OVO homolog-like 1-regulated genes, are important for hair follicle neogenesis

4 citations , April 2015 in “Experimental Dermatology”

Certain genes controlled by OVOL1 are crucial for creating new hair follicles.

research Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells

8 citations , July 2022 in “International Journal of Molecular Sciences”

17β-estradiol lowers polyamine oxidase levels in breast cancer cells through estrogen receptor 2.

Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision Between Stem Cell Maintenance and Differentiation

research Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation

1 citations , December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.

research Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas

31 citations , October 2019 in “Genes & Diseases”

Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.

JunB Defines Functional And Structural Integrity Of The Epidermal-Pilosebaceous Unit In The Skin

research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin

48 citations , August 2018 in “Nature Communications”

JunB is crucial for maintaining healthy skin and hair follicles.

research Hoxc13 polyglycine repeat gain-of-function drives mammalian integument evolution by altering targeted genes and interactions

May 2026 in “Research Square”

The polyG fragment in Hoxc13 protein helps evolve mammalian skin and hair by enhancing gene interactions.

research Runx1 transcription factor is involved in the regulation of KAP5 gene expression in human hair follicles

6 citations , January 2006 in “Journal of dermatological science”

Runx1 helps control the KAP5 gene in human hair follicles.

Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3

research Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3

December 2024 in “Animals”

RORA may help regulate hair growth by affecting hair follicle stem cells.

research Ginsenosides Rb₁ and Rd Regulate Proliferation of Mature Keratinocytes Through Induction of p63 Expression in Hair Follicles

15 citations , September 2012 in “PTR. Phytotherapy research/Phytotherapy research”

Ginsenosides Rb₁ and Rd may help prevent hair loss by promoting hair cell growth.

research Wnt-10b secreted from lymphocytes promotes differentiation of skin epithelial cells

28 citations , February 2006 in “Biochemical and Biophysical Research Communications”

Wnt-10b helps skin cells and hair grow.

Major Depletion of SOX2+ Stem Cells in the Adult Pituitary Is Not Restored and Does Not Affect Hormonal Cell Homeostasis and Remodeling

research Major depletion of SOX2+ stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling

22 citations , November 2017 in “Scientific Reports”

The pituitary gland functions normally even after losing most SOX2+ stem cells.

research M2 Macrophage and Extracellular Matrix Genes Are Enriched in High‐Activity Lichen Planopilaris

January 2025 in “Dermatology Research and Practice”

Higher activity in lichen planopilaris is linked to certain immune and tissue genes.

research MLPH-mediated activation of dermal papilla IGF-1 signaling drives human hair shaft elongation and anagen induction

February 2026 in “Biomedicine & Pharmacotherapy”

MLPH helps hair grow by activating IGF-1 signaling in hair cells.

research Image2.TIF

December 2021

GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.

research Progressive expression of PPARGC1α is associated with hair miniaturization in androgenetic alopecia

8 citations , June 2019 in “Scientific Reports”

Increased PPARGC1α relates to hair thinning in common baldness.

research Comportamiento de la estructura financiera de un grupo de empresas españolas previa a la participación del capital-riesgo

January 2008 in “Dialnet (Universidad de la Rioja)”

Certain compounds from Polygonum multiflorum roots may help treat hair loss.

research The Region Coding for the Helix Termination Motif and the Adjacent Intron 6 of the Human Type I Hair Keratin Gene hHa2 Contains Three Natural, Closely Spaced Polymorphic Sites

6 citations , March 1996 in “Journal of Investigative Dermatology”

research Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration

53 citations , April 2014 in “Experimental Dermatology”

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

research Generation of iPS-derived model cells for analyses of hair shaft differentiation

2 citations , September 2017 in “Biotechniques/BioTechniques”

Researchers created a mouse cell line to study hair growth and test hair growth drugs.

research Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer

28 citations , January 2012 in “Biological & pharmaceutical bulletin”

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

research Decision letter: Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

November 2019

S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.

research Mapping of monilethrix to the type II keratin gene cluster at chromosome 12q13 in three new families, including one with variable expressivity

21 citations , September 1997 in “British Journal of Dermatology”

Monilethrix is linked to the type II keratin gene on chromosome 12q13.

research Abstract 3372: Mouse keratinocyte side-population plays an important role during malignant progression to skin squamous cell carcinomas

3 citations , April 2012 in “Cancer research”

Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.

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