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Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

In 2005, men used finasteride mainly to treat an enlarged prostate.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.

A potential treatment for atopic dermatitis could be to increase PADI1 expression to improve skin barrier function.

Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

PAK4 is crucial in cancer progression, brain development, and could be a therapeutic target, especially through the PAK4-CREB axis.

Finasteride reduces gambling symptoms in Parkinson's patients.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.

Finasteride and dutasteride reduce prostate cancer risk, but finasteride may increase higher-grade cancer risk.

Epristeride's metabolism in zebrafish helps improve doping detection methods.

Poria cocos polysaccharides and finasteride both help treat chronic nonbacterial prostatitis, but Poria cocos polysaccharides also improve gut health.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

PAD enzymes play a key role in hair growth and structure.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

DHT affects testicular development and regulates spermatogenesis in some fish.

Finasteride effectively treats benign prostatic hyperplasia by reducing prostate size and improving urinary symptoms.

Increasing PDCD4 protein may help prevent or treat some skin cancers.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Phytosterols may help manage prostate issues but are less effective than synthetic drugs.

The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.

Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.