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research 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives

26 citations , October 2011 in “International Journal of Biological Macromolecules”

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

research 3D-printed porous functional composite scaffolds with polydopamine decoration for bone regeneration

16 citations , January 2023 in “Regenerative Biomaterials”

The scaffold with polydopamine and bioactive glass effectively promotes bone regeneration.

Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

13 citations , January 2020 in “Neuroscience”

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Inhibition of Rat Alpha-Reductases by Finasteride: Evidence for Isozyme Differences in the Mechanism of Inhibition

research Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition

98 citations , April 1997 in “The Journal of Steroid Biochemistry and Molecular Biology”

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

research Finasteride appears to be associated with an increased incidence of sexual dysfunction

May 2003 in “Reactions Weekly”

Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases

research FINASTERIDE INHIBITS 5?-REDUCTASE ACTIVITY IN HUMAN DERMAL FIBROBLASTS: PREDICTION OF ITS THERAPEUTIC APPLICATION IN ANDROGEN-RELATED SKIN DISEASES

3 citations , October 1995 in “International Journal of Dermatology”

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

research Relevance of the Axis Spermidine/eIF5A for Plant Growth and Development

19 citations , March 2016 in “Frontiers in Plant Science”

Spermidine is essential for plant growth and adaptation to stress.

research Re: Long-Term Consequences of Finasteride vs Placebo in the Prostate Cancer Prevention Trial

October 2017 in “The Journal of Urology”

Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.

research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor

86 citations , March 1993 in “Toxicology and Applied Pharmacology”

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia

research A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia

97 citations , January 2014 in “Journal of The American Academy of Dermatology”

Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.

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