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PIKFyve is essential for normal platelet function and its deficiency causes organ issues and macrophage infiltration.

Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.

Finasteride may cause pseudoporphyria, a blistering skin condition.

A teenager's hair with alternating white and dark bands, known as Pili annulati, is a genetic condition that is usually harmless and often considered attractive.

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

A rare skin condition causes red and dark patches on the face and limbs.

The man's skin condition improved with sun protection and topical steroids, but UV exposure still caused flare-ups.

PAON shows skin patterns due to genetic mosaicism.

A woman had hair loss and scalp nodules due to black piedra, confirmed by tests.

A toddler's chronic finger ulcer was successfully treated after removing a hair causing hair-thread tourniquet syndrome.

People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.

Snakes and worm lizards lost claw proteins due to similar evolutionary changes.

Trichosporon inkin and Trichosporon mucoides can cause white piedra on scalp hair.

Avoiding friction and using topical treatments can significantly improve rough skin caused by repeated rubbing.

A young boy with a rare skin and nail condition improved significantly with simple topical treatments.

Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.

Hair bands are a new symptom of facio-genito-popliteal syndrome.

A new side effect of aromatic retinoid treatment is soft nails.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

Netherton syndrome causes specific skin and hair changes that help in early diagnosis.

Jawless vertebrates have teeth proteins similar to those in mammalian hair and nails.

A rare, harmless hair condition was found in an infant's eyebrow, needing no treatment.

Long-term oral and topical treatments improved skin condition in a goldendoodle with a genetic disorder.

A mutation in the FAM83G gene is linked to skin and hair abnormalities in two related individuals.

Hair casts on the scalp may be a sign of ongoing pemphigus vulgaris and could suggest a need to adjust treatment.

Frequent hairdryer use may worsen hair fragility in people with Pili Annulati.

A 90-year-old woman's hand lesion was a rare, aggressive skin cancer treated successfully with surgery.

Sorafenib may cause hand-foot and stump syndrome, requiring early detection and management.

Club-like receptors detect light touch but not whisking.