research Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche
Different types of stem cells and their environments are key to skin repair and maintenance.
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research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Melatonin and the hair follicle
Melatonin helps regulate hair growth and protects the hair follicle from stress.
research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research An integrative view of mammalian seasonal neuroendocrinology
The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
research KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin
EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research Female Pattern Hair Loss and its Relationship to Permanent/Cicatricial Alopecia: A New Perspective
Some women with common hair loss may develop permanent hair loss.
research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice*
Prolactin affects when mice shed and grow hair.
research Endocrine Influences on Hair Growth
Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling
Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
research Normal Hair Growth in Children
Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.
research The prostamide‐related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias
Bimatoprost, a glaucoma medication, may also help treat hair loss.
research Effect of constant-release melatonin implants and prolonged exposure to a long day photoperiod on prolactin secretion and hair growth in mouflon (Ovis gmelini musimon)
Melatonin implants and long daylight hours alter the timing of hormone release and hair growth in mouflon sheep.
research A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats
A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
research The hair cycle and its regulation
Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.
research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis
Mice without certain skin proteins had abnormal skin and hair development.
research Hair follicle elongation in organ culture of skin from newborn and adult mice
Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.
research Hoxc13/β-catenin Correlation with Hair Follicle Activity in Cashmere Goat
Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.
research Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice
Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes
Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
research Dermal-epidermal interactions—follicle-derived cell populations in the study of hair-growth mechanisms
Dermal-epidermal interactions are crucial for hair growth and maintenance.
research Characterization and causal investigations of an alopecia syndrome in Australian fur seals (Arctocephalus pusillus doriferus)
Young female Australian fur seals are losing hair due to low tyrosine and zinc levels and high pollution exposure.
research CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth
Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
research Exogen involves gradual release of the hair club fibre in the vibrissa follicle model
Hair sheds gradually from the follicle, with readiness to shed indicated by less attachment material.
research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice
Prolactin affects when mice shed and grow hair.
research Lack of Response to Laser Comb in Spontaneous and Graft-Induced Alopecia Areata in C3H/HeJ Mice
The laser comb did not improve hair regrowth in mice with alopecia areata.
research Environmental Influences on the Hair Follicle
Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.