December 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.
1 citations
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April 2021 in “Clinical, Cosmetic and Investigational Dermatology” Conflicting findings in androgenic alopecia are likely due to biopsy location, hair diameter diversity, and hair follicle miniaturization.
288 citations
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June 2009 in “Human reproduction update” The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.
110 citations
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October 2019 in “Translational Andrology and Urology” More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
August 2025 in “International Journal of Cancer” Childhood and adult height, and early immune-related hospitalizations increase testicular cancer risk, while baldness, larger families, and sports reduce it.
13 citations
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January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
November 2020 in “Reactions Weekly” Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.
Certain medications, especially 5-alpha reductase inhibitors, are commonly linked to erectile dysfunction.
People with early-onset hair loss (AGA) have a higher risk of heart disease, metabolic syndrome, and prostate enlargement.
48 citations
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April 1995 in “PubMed” Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.
28 citations
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May 1998 in “Skin Research and Technology” Scalp flaps are stiffer than skin from other body areas, which helps in planning reconstructive and cosmetic head surgeries.
January 2001 in “대한피부과학회지” Horizontal sectioning helps diagnose hair loss, but Korean follicle differences matter.
1 citations
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June 2017 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride use may cause sexual dysfunction; more research needed.
May 2025 in “InnovAiT Education and inspiration for general practice” Male pattern hair loss is common, affects mental health, and can be treated with medication or hair transplants.
12 citations
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November 2019 in “PLoS ONE” Male-pattern baldness is weakly linked to some heart disease risk factors but not a strong indicator for heart disease.
15 citations
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June 1995 in “The American Journal of the Medical Sciences” Finasteride caused enlarged breast tissue in a 62-year-old man.
1 citations
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January 2015 in “Sexual Medicine Reviews” Current treatments for recurrent ischemic priapism are not well-defined and need more research.
September 2025 in “Toxicology” Long-term use of finasteride and minoxidil may harm male reproductive health in mice.
17 citations
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December 2004 in “The Journal of Men's Health & Gender” Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
August 2023 in “International journal of impotence research” Many dermatologists believe finasteride can cause sexual side effects and counsel patients about them.
March 2015 in “The Journal of Urology” Finasteride reduces PSA levels by around 40-50% in BPH patients.
41 citations
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March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
3 citations
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November 2019 in “The American Journal of Dermatopathology” Widened sweat ducts are a very specific sign of scarring hair loss.
58 citations
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December 2018 in “Nature Communications” Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
2 citations
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September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
124 citations
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April 1992 in “Journal of Endocrinology/Journal of endocrinology” Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
December 2015 in “Вестник дерматологии и венерологии” Men with male pattern baldness may not have different hormone levels, but their hair follicles are likely more sensitive to hormones.
The modified Sinclair scale effectively measures hair loss severity in men.
18 citations
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June 2009 in “Journal of Molecular Endocrinology” Finasteride exposure harms tadpole reproduction and hormone balance.