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Midazolam Ameliorates the Behavioral Deficits of a Rat Posttraumatic Stress Disorder Model Through Dual 18 kDa Translocator Protein and Central Benzodiazepine Receptor and Neurosteroidogenesis

research Midazolam Ameliorates the Behavior Deficits of a Rat Posttraumatic Stress Disorder Model through Dual 18 kDa Translocator Protein and Central Benzodiazepine Receptor and Neurosteroidogenesis

56 citations , July 2014 in “PLoS ONE”

Midazolam reduces PTSD-like behavior in rats by acting on specific brain receptors.

research Management of Hirsutism

55 citations , March 2000 in “American journal of clinical dermatology”

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

research Therapeutic approach for metabolic disorders and infertility in women with PCOS

54 citations , August 2017 in “Gynecological Endocrinology”

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

research Finasteride use in the male infertility population: effects on semen and hormone parameters

54 citations , September 2013 in “Fertility and Sterility”

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16

53 citations , September 1999 in “The journal of cell biology/The Journal of cell biology”

K16 can partially replace K14 but causes hair loss and skin issues.

research 8 Hair follicles and associated glands as androgen targets

53 citations , May 1986 in “Clinics in endocrinology and metabolism”

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

research Influence of spironolactone treatment on endothelial function in non-obese women with polycystic ovary syndrome

50 citations , March 2011 in “European Journal of Endocrinology”

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

research A prospective, randomized trial comparing flutamide (250 mg/d) and finasteride (5 mg/d) in the treatment of hirsutism

50 citations , May 2000 in “Fertility and Sterility”

Flutamide reduces hair growth better but has more side effects.

research The effect of spironolactone on genital skin 5α-reductase activity

50 citations , August 1985 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

research Novel skin patch combining human fibroblast-derived matrix and ciprofloxacin for infected wound healing

49 citations , January 2018 in “Theranostics”

The new skin patch with human matrix and antibiotic improves wound healing.

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