105 citations
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January 2009 in “Medicine” Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
15 citations
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October 2014 in “Hormone Molecular Biology and Clinical Investigation” Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
99 citations
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August 2003 in “Fertility and Sterility” Too much male hormone is the main cause of Polycystic Ovary Syndrome.
51 citations
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April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
49 citations
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September 1986 in “British Journal of Dermatology” Hidradenitis suppurativa improves with antiandrogen therapy.
34 citations
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July 2020 in “Frontiers in immunology” Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
31 citations
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November 2014 in “Journal of Endocrinological Investigation” Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
8 citations
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April 2019 in “Journal of the Endocrine Society” Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
5 citations
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January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
4 citations
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April 2016 in “Journal of Dermatology Research and Therapy” Anti-androgens are safe and effective for treating moderate to severe adult female acne.
February 2024 in “Malahayati Nursing Journal” High androgen levels can cause hirsutism and increase inflammation.
63 citations
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November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
5 citations
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December 1979 in “Clinical and Experimental Dermatology” Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
41 citations
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November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
9 citations
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June 2002 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.
378 citations
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November 2011 in “Human reproduction update” Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
52 citations
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June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
48 citations
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February 2008 in “Nutrition in Clinical Practice” Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.
41 citations
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September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
40 citations
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February 2005 in “Fertility and Sterility” Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.
34 citations
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February 2016 in “Fertility and Sterility” More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.
25 citations
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June 2019 in “Endocrine Related Cancer” Mutations in certain receptors can cause diseases and offer new treatment options.
24 citations
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September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
14 citations
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January 2018 in “Endocrinology and Metabolism” Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.
14 citations
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September 2014 in “Journal of Pediatric and Adolescent Gynecology” Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.
13 citations
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July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
12 citations
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January 2016 in “Endocrinology, diabetes & metabolism case reports” Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.