May 2024 in “Scientific Reports” Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
February 2021 in “International Journal of Science and Research (IJSR)” A higher testosterone/dihydrotestosterone ratio in PCOS patients may indicate worse metabolic health.
23 citations
,
December 2017 in “Scientific Reports” ARL15 is important for fat cell development and the release of the hormone adiponectin.
14 citations
,
December 2016 in “Sexual Medicine” Finasteride side effects in young men may be linked to specific gene variations.
14 citations
,
December 2010 in “Seminars in Oncology” Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.
10 citations
,
December 2015 in “Clinics in Dermatology” Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
6 citations
,
December 2020 in “Dermatological reviews” COVID-19 may worsen with androgens; anti-androgen drugs could help.
1 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” Hypothyroidism may worsen metabolic problems like insulin resistance and obesity in women with PCOS.
1 citations
,
April 2006 in “Seminars in Reproductive Medicine” Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
April 2026 in “JOJ Dermatology & Cosmetics” Skin issues in PCOS signal hormone problems, and combined treatments improve outcomes.
16 citations
,
April 2007 in “Journal of Obstetrics and Gynaecology Research” Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.
16 citations
,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
70 citations
,
March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
45 citations
,
February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
40 citations
,
December 2016 in “Journal of Ovarian Research” Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
8 citations
,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Mild thyroid issues don't affect the metabolism and hormones of women with PCOS.
4 citations
,
October 2019 in “Case Reports” A 33-year-old woman with PCOS and metabolic syndrome was unusually diagnosed with a bone condition called DISH, suggesting a possible link between these conditions.
3 citations
,
June 2025 in “Drug Design Development and Therapy” Targeting glycolysis may help treat PCOS by improving insulin sensitivity and ovarian function.
1 citations
,
October 2020 in “Journal of Cosmetic Dermatology” Possible link between hair loss and metabolic syndrome, with RANTES as a potential clue.
August 2015 in “Postgraduate obstetrics & gynecology” Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.
August 2015 in “Postgraduate obstetrics & gynecology” Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.
Older age, obesity, hirsutism, and having children increase metabolic risk in women with PCOS.
69 citations
,
December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
7 citations
,
January 2018 in “Reproduction” Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
1 citations
,
January 2017 in “Przegla̧d dermatologiczny” People with more than 11 skin tags, especially on the thigh, neck, or armpit, may have a higher chance of metabolic syndrome.
Men with androgenetic alopecia may have a higher risk of metabolic syndrome.
33 citations
,
September 2014 in “Reproductive Biology and Endocrinology” High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
16 citations
,
May 2013 in “Urology” Metabolic syndrome linked to urinary symptoms; hair loss not significant.
7 citations
,
February 2016 in “Arab journal of urology” People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.