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Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

A woman's masculine symptoms were caused by a rare tumor in her left ovary, which was found using a special blood test.

The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Postmenopausal women with excess male hormones may have ovarian tumors, and surgery usually cures them.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

A new system helps better diagnose and treat female androgenization conditions like PCOS.

Combined finasteride and anastrozole therapy effectively treats BPH, influenced by hormone imbalances and genetics.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.

Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Women with hair loss have more androgen receptors in certain hair follicles.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Blocking androgen receptors boosts macrophages' ability to clear certain bacteria.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

GnRH agonist effectively diagnoses and treats postmenopausal hyperandrogenism from ovarian sources.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.

Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Androgen receptor abnormalities may contribute to hair loss in androgenetic alopecia.

A woman developed male characteristics after using unregulated hormone therapy.

A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.

A woman's hyperandrogenism was caused by a genetic mutation leading to non-classic adrenogenital syndrome.

Ectopic adrenal rests can cause androgen excess after adrenalectomy and may need targeted surgery.