3 citations
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November 2021 in “Journal of The American Academy of Dermatology” Androgenetic alopecia, a genetic disorder affecting up to 50% of adults, is caused by an excessive response to androgens leading to hair follicle shrinkage. Treatments include FDA-approved drugs, other therapies like low-dose oral minoxidil, and hair transplantation.
May 2023 in “Frontiers in Endocrinology” Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
January 2004 in “Pharmaceutical biotechnology” Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.
June 2023 in “Clinica Chimica Acta” Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.
60 citations
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June 2007 in “Pharmacology Biochemistry and Behavior” Blocking progesterone metabolism can cause depression-like behavior in mice.
November 2007 in “Neuro-chirurgie/Neurochirurgie” Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.
17 citations
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January 2023 in “Frontiers in Pharmacology” 2Br-Crebanine and Stephanine reduce inflammation and pain effectively.
2 citations
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December 2001 in “Dermatologic Therapy” Steroids may not work well for alopecia areata because of high unoccupied receptors and low thioredoxin levels.
280 citations
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January 2004 in “The EMBO Journal” AGC2-1 protein is essential for root hair growth in Arabidopsis.
December 2023 in “European Journal of Medicinal Chemistry” Natural products might be safe, effective, and affordable treatments for hair loss.
December 2019 in “Reactions Weekly” Man stopped medications due to sexual side effects, found relief with prostatic artery embolisation.
20 citations
,
February 2017 in “European journal of pharmaceutical sciences” The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.
5 citations
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July 2011 in “PubMed” Injected bimatoprost 0.03% solution did not effectively treat female-pattern hair loss.
6 citations
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September 2010 in “Current Urology Reports” New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.
40 citations
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July 2023 in “Clinical Pharmacology & Therapeutics” Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.
42 citations
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March 2014 in “European Journal of Pharmacology” Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.
6 citations
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September 2023 in “Experimental physiology” A special receptor in sensory nerve endings helps control how they respond to stretching.
December 2015 in “PLOS ONE” October 2006 in “Urology” The study found that different criteria led to different patient groups in the CombAT study compared to the MTOPS study.
August 2010 in “Oncology Times” Provenge extends prostate cancer survival by about 4 months.
May 2005 in “Molecular Carcinogenesis” mrp/plf-mRNA can indicate tumor-promoting effects in skin.
July 2013 in “Faculty of Health; Institute of Health and Biomedical Innovation” Prostaglandins don't genetically contribute to hair loss.
May 2026 in “Journal of Nanobiotechnology” A new peptide delivered through microneedles can effectively promote hair regrowth.
24 citations
,
November 2015 in “Frontiers in Genetics” Nitroxide drugs can safely and effectively treat age-related diseases like macular degeneration and cardiovascular issues.
47 citations
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January 2003 in “Current opinion in urology” A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
April 2017 in “The Journal of urology/The journal of urology” Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
3 citations
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January 2018 in “Reproduction, Fertility and Development” Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
January 2007 in “Journal of Clinical Dermatology” The topical solution increased hair count but wasn't significantly better than placebo in other measures.
November 2025 in “Food Science & Nutrition” Apigenin may effectively promote hair growth for androgenetic alopecia when applied topically.