research Lipid nanoparticles for topical and transdermal delivery of pharmaceuticals and cosmeceuticals
Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.
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research The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
research A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia
MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
research Cross‐Sex Hormone Therapy in Trans Persons Is Safe and Effective at Short‐Time Follow‐Up: Results from the European Network for the Investigation of Gender Incongruence
Hormone therapy for trans individuals is effective and generally safe in the short term.
research Liposomal systems as drug delivery vehicles for dermal and transdermal applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors
EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Liposomes and niosomes as potential carriers for dermal delivery of minoxidil
Liposomes better deliver minoxidil for hair loss treatment than niosomes.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
research Niosomes as a propitious carrier for topical drug delivery
Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
research Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes
Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
research Combined Sabal and Urtica extract vs finasteride in BPH (Alken stage I–II)
Sabal and Urtica extract works as well as finasteride for treating BPH, with fewer side effects.
research Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research What do we know about phytotherapy of benign prostatic hyperplasia?
Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.
research Pulmonary Edema in COVID-19 Patients: Mechanisms and Treatment Potential
Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.
research Alisertib is active as single agent in recurrent atypical teratoid rhabdoid tumors in 4 children
Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.
research Effects of minoxidil on hemodynamics in patients with congestive heart failure.
Minoxidil improves blood flow in heart failure patients.
research Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Recent advances in nanocarrier-loaded gels: Which drug delivery technologies against which diseases?
Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
research Management of Hirsutism
Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
research A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido
DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.
research 11β-Hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
research Androgens and Antiandrogens
Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
research Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research Complementary and Alternative Treatments for Alopecia: A Comprehensive Review
Some alternative treatments for hair loss might work, but more research is needed.
research Topical ketoconazole: a systematic review of current dermatological applications and future developments
Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
research Modern drug delivery strategies applied to natural active compounds
New drug delivery methods can make natural compounds more effective and stable.
research Side effects of common acne treatments
Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.