95 citations
,
July 2006 in “British Journal of Dermatology” Vitamin D receptors in hair follicles change with the hair cycle, affecting hair growth.
94 citations
,
July 2003 in “Journal of biological chemistry/The Journal of biological chemistry” EGF controls hair growth by regulating hair follicles' growth phases.
94 citations
,
August 1975 in “Journal of Cutaneous Pathology” Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.
92 citations
,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
92 citations
,
September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
91 citations
,
April 2011 in “Journal of Ethnopharmacology” Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.
91 citations
,
May 2003 in “American Journal of Pathology” Prolactin affects hair growth cycles and can cause early hair follicle regression.
90 citations
,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
90 citations
,
October 1983 in “British Journal of Dermatology” The unit area trichogram is a reliable method to assess hair loss and treatment response in people with androgenic alopecia by measuring hair density and thickness.
88 citations
,
June 2019 in “Cell reports” Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
88 citations
,
February 2011 in “Journal of Dermatological Science” Minoxidil helps hair growth by activating the β-catenin pathway.
88 citations
,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
87 citations
,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
86 citations
,
August 2000 in “Pigment cell research” Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
83 citations
,
May 1999 in “International Journal of Dermatology” Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
82 citations
,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
81 citations
,
July 2011 in “Lasers in Medical Science” The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.
81 citations
,
December 2009 in “Journal of Dermatological Science” Fat tissue stem cells may help increase hair growth.
81 citations
,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
76 citations
,
March 2005 in “Journal of Molecular Medicine” Certain mice without specific receptors or mast cells don't lose hair from stress.
72 citations
,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
72 citations
,
January 2012 in “Annals of Dermatology” IGF-I promotes hair growth by keeping hair follicles in the growth phase longer.
72 citations
,
February 2011 in “American Journal of Biological Anthropology” The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.
72 citations
,
November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
71 citations
,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
71 citations
,
June 2007 in “Bioorganic & Medicinal Chemistry Letters” PLGA nanospheres improve hair growth by effectively delivering ingredients to hair follicles.
71 citations
,
February 2006 in “Clinics in Dermatology” Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.
71 citations
,
June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
71 citations
,
January 1998 in “Pathobiology” The document concludes that certain rats and mice are useful for studying hair loss in humans and testing treatments.
70 citations
,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.