research 28‐Day Repeated Dose Toxicity and Toxicokinetics Study on Dihydroartemisinin (DHA) in SD Rats
High doses of dihydroartemisinin caused reversible liver toxicity in rats, with females more affected than males.
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research 187 Protective Effect of DA-9401 on Acute use of Finasteride on Sprague–Dawley Rats
DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.
research Finasteride, a 5alpha-reductase enzyme inhibitor, alone and synergism with a neurosteroid reduces responsiveness to nociceptive stimuli in male rat
Finasteride reduces pain in male rats and works better with testosterone.
research Finasteride
research Finasteride
research The patient journey in prurigo nodularis: what lies ahead
Prurigo nodularis (PN) is a chronic skin disorder marked by intensely itchy nodules that significantly impact patients' quality of life. Although recent advances have been made in understanding its neuroimmune pathogenesis and developing targeted biologics like dupilumab and nemolizumab, PN remains under-recognized and difficult to diagnose and manage. Traditional treatments have been empirical, but newer biologics show promise in reducing itch and improving skin condition. There are unmet needs in diagnosis and management, especially for adolescents and children, and more real-world data and long-term studies are necessary. The patient journey is complicated by the need for multidisciplinary care and the psychological impact of the disease, emphasizing the importance of patient education and shared decision-making in treatment plans.