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Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

The new method is 1000 times more sensitive for measuring hair growth.

Using focused ultrasound on the brain can help epilepsy medicine work better in rats.

FTase and GGTase-I are essential for skin keratinocyte health.

The process effectively regenerates the Pd/C catalyst for finasteride synthesis.

The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.

Localized ROS production is essential for cell growth and movement in plants and animals.

Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.

PTeCA is a reliable marker for detecting oxidative hair treatments.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Improving PROTAC delivery systems can enhance their effectiveness and speed up their use in medicine.

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.

The new formulation greatly improved quercetin absorption in rats.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.