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Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.

Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.

BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.

Ptprq has multiple forms that change during inner ear development.

Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

ICP5249 helps hair grow by activating a specific cell pathway.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.

Keratinocytes can reverse the effects of the GNAQ oncogene, inhibiting melanoma cell growth.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

PAK4 is crucial in cancer progression, brain development, and could be a therapeutic target, especially through the PAK4-CREB axis.

The frizzy mouse and hairless rat mutations are due to changes in the Prss8 gene.

Phosphatidylinositol 4-kinases are crucial for root growth, defense, and immunity in Arabidopsis thaliana.

Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.

Lack of KSR1 stops certain skin tumors in mice.

The scant hair in snthr-1Bao mice is likely caused by a deletion affecting the Plcd1 gene.

Changing YBX1 protein activity affects skin stem cell function and aging.

The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.

GLABRA2 gene controls root-hair growth by regulating phospholipid signaling.

KAP6 genes are conserved across species and active in hair follicles.

Serine is vital for hair follicle stem cells to balance hair growth and skin repair.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Lower SMAD2/3 activation predicts more severe skin cancer.

Phospholipases help maintain and restore skin and hair health, potentially leading to new treatments for related conditions.

GLABRA2 represses root hair formation by inhibiting a specific gene.