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Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

13 citations , January 2020 in “Neuroscience”

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

research Co-loading of finasteride and baicalin in phospholipid vesicles tailored for the treatment of hair disorders

13 citations , January 2020 in “Nanoscale”

Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.

research Genetically Induced Cell Death in Bulge Stem Cells Reveals Their Redundancy for Hair and Epidermal Regeneration

13 citations , December 2014 in “Stem Cells”

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Exploring the Therapeutic Potential of TGF-Beta Inhibitors for Liver Fibrosis: Targeting Multiple Signaling Pathways

research Exploring the Therapeutic Potential of TGF-β Inhibitors for Liver Fibrosis: Targeting Multiple Signaling Pathways

12 citations , July 2025 in “Journal of Clinical and Translational Hepatology”

TGF-β inhibitors may help treat liver fibrosis by targeting various pathways.

research Glutamic acid promotes hair growth in mice

12 citations , July 2021 in “Scientific Reports”

Glutamic acid helps increase hair growth in mice.

research Androgen Receptor in Human Health: A Potential Therapeutic Target

12 citations , December 2012 in “Current Drug Targets”

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

research Acute sensitivity of the oral mucosa to oncogenic K‐ras

12 citations , March 2011 in “Journal of pathology”

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

research Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

11 citations , September 2019 in “Dermatologic Surgery”

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

research Human platelet lysate versus minoxidil stimulates hair growth by activating anagen promoting signaling pathways

11 citations , October 2016 in “Biomedicine & Pharmacotherapy”

Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.

Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ

research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ

11 citations , July 2015 in “Gene”

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

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