research Melanocytes: The new Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
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research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research Pyrene Excimer Nucleic Acid Probes for Biomolecule Signaling
Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.
research Protoporphyrin IX: the Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Repigmentation through Melanocyte Regeneration in Vitiligo
UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis - eScholarship
Retinoids can help treat skin pigmentation disorders by affecting melanin production.
research Estudo da diversidade dos genes MC1R e SLC24A5 em populações globais: avaliação de aspectos evolutivos e ambientais
SLC24A5 shows a clear selective sweep, but no link to UV radiation intensity.
research Pigmentation of regenerated hairs after wounding
Regenerated hairs can regain their color if the wound occurs during a certain stage of hair growth, and this process is helped by specific skin cells and proteins.
research NON-PSORALEN TREATMENT OF VITILIGO. PART II. LESS COMMONLY USED AND EXPERIMENTAL THERAPIES
Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.
research Dermal Papilla Cells and Melanocytes Response to Physiological Oxygen Levels Depends on Their Interactions
Oxygen levels affect hair growth and color cells differently when they interact directly.
research Skin Hyperpigmentation in Complex Regional Pain Syndrome (CRPS) (P3.315)
Skin pigmentation increases in CRPS-affected areas and improves with symptom relief.
research Multicolor Hair Dyeing with Biocompatible Dark Polyphenol Complex-Integrated Shampoo with Reactive Oxygen Species Scavenging Activity
The new hair-dyeing shampoo is safe, colors hair evenly, and strengthens it.
research Clinical Snippets
Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
research 1360 Regulation of bmp signalling in melanogenesis, pigment transfer and melanocyte migration
BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
research Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment
The technique can isolate cells to help treat skin pigmentation issues.
research Predicting hair cortisol levels with hair pigmentation genes: a possible hair pigmentation bias
Darker hair may lead to higher cortisol readings, suggesting a need to adjust for hair color in studies.
research Early skin seeding regulatory T cells modulate PPARγ-dependent skin pigmentation
Early regulatory T cells are crucial for normal skin pigmentation.
research SASH1 Mutations and Hereditary Disorders of Pigmentation: Review of Literature
SASH1 gene mutations are linked to various inherited skin pigmentation disorders.
research Targeted photosensitizer delivery: A prospective approach to vitiligo photochemotherapy
The method could improve vitiligo treatment by effectively delivering therapy to hair follicles.
research IMMUNOHISTOCHEMICAL DEMONSTRATION OF POLY(ADENOSINE DIPHOSPHATE‐RIBOSE) SYNTHESIS IN HUMAN SKIN
Poly(ADP-ribose) synthesis is linked to skin cell differentiation.
research An open-access data set of pig skin anatomy and physiology for modelling purposes
The data set helps improve predictions of how substances are absorbed through pig skin.
research High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
research Untersuchungen der Fremdstoffbindung in permanenten Keratinozyten- und Melanozyten-Zelllinien sowie die Eignung von Primärkulturen aus humanen Haarfollikeln zur In-vitro-Messung der Fremdstoffaufnahme im Haar
Unpigmented keratinocytes absorb substances faster, while melanocytes bind more strongly to melanin.
research In vivo multiphoton microscopy imaging of vitiligo (Conference Presentation)
Multiphoton microscopy helps understand and improve vitiligo treatments by visualizing skin cell changes.
research Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders
Pluripotent stem cells show promise for treating skin color loss disorders like vitiligo.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research THE CHEMISTRY MECHANISM OF HAIR DYES
Permanent hair dyes use chemicals that react with hydrogen peroxide to create color.
research Difference Between Pigmented and Nonpigmented Skin
Skin diseases look different on pigmented and nonpigmented skin.
research Percutaneous penetration of hair dyes
Hair dyes penetrate the scalp very minimally, less than 1%.
research Hair Coloration by Gene Regulation: Fact or Fiction?
Gene regulation could revolutionize hair color by altering pigmentation from within.