May 2021 in “Open Access Macedonian Journal of Medical Sciences” People with premature hair graying have an imbalance between harmful and protective molecules in their body, hinting that antioxidants might help.
141 citations
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January 1984 in “Journal of The American Academy of Dermatology” Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.
93 citations
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February 2015 in “Journal of Investigative Dermatology” Oxidative stress affects hair loss in men with androgenetic alopecia.
87 citations
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July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
70 citations
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March 2016 in “Urologic Clinics of North America” The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
64 citations
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June 1992 in “International Journal of Dermatology” Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
8 citations
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April 2020 in “Facial Plastic Surgery Clinics of North America” Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
30 citations
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July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
127 citations
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December 2005 in “Experimental Dermatology” Stress can stop hair growth in mice, and treatments can reverse this effect.
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May 2021 in “Scientific Reports” Stress is likely causing hair loss in Formosan macaques.
85 citations
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August 2018 in “Psychological Medicine” Women with PCOS are more likely to suffer from depression, anxiety, and stress.
269 citations
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May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
127 citations
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July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
126 citations
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January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
123 citations
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May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
96 citations
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January 1997 in “Clinics in Dermatology” Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.
65 citations
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May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
43 citations
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August 2016 in “International Journal of Nanomedicine” Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
37 citations
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June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
28 citations
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May 2015 in “Addiction Biology” Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
11 citations
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March 2019 in “EMBO molecular medicine” A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.
9 citations
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August 2017 in “Photochemistry and Photobiology” Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
7 citations
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January 2020 in “Postepy Dermatologii I Alergologii” Oxidative stress plays a role in female pattern baldness, causing an imbalance between harmful and protective elements in the body.
6 citations
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April 2015 in “Behavioural Brain Research” Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.
5 citations
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July 2021 in “Basic & Clinical Pharmacology & Toxicology” Melatonin may protect ear cells from damage caused by nicotine.
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February 2022 in “Frontiers in molecular biosciences” Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
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June 2023 in “Frontiers in medicine” Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.
3 citations
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January 2015 in “Turkiye Klinikleri Journal of Medical Sciences” Corticosteroids may not effectively control oxidative stress in alopecia areata, possibly leading to relapses.
2 citations
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November 2025 in “Journal of Ovarian Research” Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.