31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
4 citations
,
April 1999 in “Dermatologic Clinics” Androgens, like DHT, affect hair growth and treatments like finasteride may help.
15 citations
,
October 2014 in “Hormone Molecular Biology and Clinical Investigation” Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
39 citations
,
April 2007 in “Therapeutic Drug Monitoring” Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
1341 citations
,
January 2014 in “Cardiology Research and Practice” Managing metabolic syndrome needs both lifestyle changes and medical treatments.
127 citations
,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
65 citations
,
August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
81 citations
,
November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
15 citations
,
January 2024 in “The AAPS Journal” 50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.
4 citations
,
October 2022 in “Frontiers in public health” Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Red light exposure can slow aging in mice by improving fat metabolism.
January 2026 in “Annals of Clinical Endocrinology and Metabolism” Restoring NAD⁺ may help with aging and chronic diseases, but more research is needed.
January 2026 in “Food Science and Human Wellness” Krill oil may help reduce prostate enlargement and growth.
January 2026 in “RSC Advances” Epristeride's metabolism in zebrafish helps improve doping detection methods.
26 citations
,
August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
24 citations
,
July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
6 citations
,
September 2012 in “Clinical Interventions in Aging” Honokiol might help reduce male skin aging by maintaining testosterone levels.
24 citations
,
June 2011 in “International Journal of Dermatology” Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.
2 citations
,
January 2020 in “BioMed Research International” Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
1 citations
,
January 2018 in “Recent clinical techniques, results, and research in wounds” Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
67 citations
,
February 2020 in “Journal of Ginseng Research” Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.
5 citations
,
October 2014 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
36 citations
,
October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
23 citations
,
December 2017 in “Scientific Reports” ARL15 is important for fat cell development and the release of the hormone adiponectin.
22 citations
,
October 2012 in “Journal of Investigative Dermatology” Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
19 citations
,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
2 citations
,
November 2019 in “Cancer reports” The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
1 citations
,
July 2022 in “Functional foods in health and disease/Journal of functional foods in health & disease” Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.
January 2025 in “Fitoterapia” Signaling pathways are key targets for developing effective drugs.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.